Results 191 to 200 of about 362,423 (312)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Raising the Floor? Genetic Influences on Educational Attainment Through the Lens of the Evolving Swedish Welfare State. [PDF]

Behav Genet
Pettersson O.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Husbandry Conditions and Welfare State of Pet Chinchillas (Chinchilla lanigera) and Caretakers' Perceptions of Stress and Emotional Closeness to Their Animals. [PDF]

Animals (Basel)
Gilhofer EM, Hebesberger DV, Waiblinger S, Künzel F, Rouha-Mülleder C, Mariti C, Windschnurer I.   +6 more
europepmc   +1 more source

Radical right parties and their welfare state stances - not so blurry after all? [PDF]

West Eur Polit, 2022
Enggist M, Pinggera M.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Reproductive justice for the haunted Nordic welfare state: Race, racism, and queer bioethics in Finland. [PDF]

Bioethics, 2022
Sudenkaarne T, Blell M.
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Food Insecurity and Social Policy: A Comparative Analysis of Welfare State Regimes in 19 Countries. [PDF]

Int J Soc Determinants Health Health Serv
Berkowitz SA, Drake C, Byhoff E.
europepmc   +1 more source