Results 71 to 80 of about 1,936,269 (327)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

The Paradigmatic Struggle for Legitimacy of the Danish Welfare State regarding the Provision of Welfare Services - Taking care of vulnerable children and youths as a core problem

open access: yesNordicum-Mediterraneum, 2014
The Danish welfare state constitutes a paradigmatic case of the welfare struggle of modern welfare states. Taking care of vulnerable children and youths is used as a case study here, to illustrate the efforts of the welfare state to acquire legitimacy as
John Storm Pedersen   +2 more
doaj  

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Dignity and the Burden of the Welfare State [PDF]

open access: yes
The burden of the welfare state may be analysed from an economic as well as a more normative perspective. This paper attempts to do both things. By the use of the case of Sweden the expansion and the costs of the welfare state is described, partly in ...
Karlson, Nils
core  

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

State Intervention in Economy. From Minimal State to Welfare State

open access: yesActa Universitatis Danubius: Administratio, 2012
Contemporary crisis brought new challenges for policy-makers. Alarming increase in public spending, combined with a high level of debt has forced the governments to seek new ways to intervene in the economic activity, without affecting normal economic ...
Florin Marius Popa
doaj  

Ideologi Welfare State Dalam Dasar Negara Indonesia: Analisis Putusan Mahkamah Konstitusi Terkait Sistem Jaminan Sosial Nasional [PDF]

open access: yes, 2012
Are the objective of Indonesia “promoting the general welfare”, and the fifth principle of Pancasila “social justice for all people of Indonesia”, as well as the constitutional mandate to hold a social security system must be expressed in terms of the ...
Alfitri, A. (Alfitri)
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Liberalism’s Difficult Relationship with the Welfare State

open access: yesErasmus Journal for Philosophy and Economics
This paper makes two related points. First, as liberals have started to realize that the welfare state is unable to deliver on egalitarian theories of justice, they have increasingly tried to dissociate their theories from the welfare state.
Harald Borgebund
doaj   +1 more source

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