Results 71 to 80 of about 27,143,692 (378)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Factor structure of the happiness-increasing strategies scales (H-ISS): activities and coping strategies in relation to positive and negative affect [PDF]

open access: yesPeerJ, 2015
Background. Previous research (Tkach & Lyubomirsky, 2006) shows that there are eight general happiness-increasing strategies: social affiliation, partying, mental control, goal pursuit, passive leisure, active leisure, religion, and direct attempts.
Ali Al Nima, Danilo Garcia
doaj   +2 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Development of tight junction-strengthening compounds using a high-throughput screening system to evaluate cell surface-localized claudin-1 in keratinocytes

open access: yesScientific Reports
Tight junctions (TJs) are important factors constituting the physical barriers of the skin, and their suppression has been described in various conditions, such as aged skin and atopic dermatitis lesions.
Hiroki Sakamoto   +2 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Satisfaction and frustration: the well-being experience of homemade knitwear [PDF]

open access: yes, 2013
This paper considers well-being in relation to homemade knitted garments. The topic forms part of a qualitative design research project investigating amateur making as a sustainable fashion strategy.
Twigger Holroyd, A
core  

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Well-being interventions - do they actually work during critical organisational change? [PDF]

open access: yes, 2016
The research findings suggest that there are benefits to be gained from investing in employee well-being - even during the most difficult of circumstances – as such interventions will still have a positive impact on employees’ physical and mental health ...
Evans, Samantha
core  

Teachers’ well-being

open access: yesOECD Education Working Papers, 2020
Modern education systems evolve in a context of growing teacher shortages, frequent turnover and a low attractiveness of the profession. In such a context where these challenges interrelate, there is an urgent need to better understand the well-being of ...
Carine Viac, P. Fraser
semanticscholar   +1 more source

Music and well-being

open access: yesThe Journal for Transdisciplinary Research in Southern Africa, 2014
This paper scrutinizes how human beings relate to the wider cosmos in the thinking of the European Middle Ages. The re-invention of the ‘spiritual’ might liberate Western culture from Cartesian elements within Western Christianity and the consequent limited and exclusive views of musicking.
openaire   +5 more sources

Home - About - Disclaimer - Privacy