Results 61 to 70 of about 14,206,500 (165)

Rare aggressive behavior of MDM2-amplified retroperitoneal dedifferentiated liposarcoma, with brain, lung and subcutaneous metastases

Rare Tumors, 2016
Dedifferentiated liposarcoma (DDL) is a histologically pleomorphic sarcoma, traditionally defined as well-differentiated liposarcoma with abrupt transition to high grade, nonlipogenic sarcoma.
Imen Ben Salha, Shane Zaidi, Jonathan Noujaim, Aisha B. Miah, Cyril Fisher, Robin L. Jones, Khin Thway   +6 more
doaj   +1 more source

Cytoskeletal Dynamics in Cancer: From Pathogenesis to Treatment

MedComm, Volume 7, Issue 10, October 2026.
This review systematically addresses the fundamental roles of the cytoskeleton (actin filaments, microtubules, and intermediate filaments) in cancer progression. We focus on how cytoskeletal dynamics regulate tumor proliferation, metastasis, and programmed cell death, while also modulating the immune microenvironment. Understanding these mechanisms may
Jie Chen, Wenxi Yang, Yonghan Song, Yuanhao Zhang, Jia Ma, Tingyao Wang, Jijun Zheng, Hebin Zhang, Yiyao Liu, Jinhao Zeng   +9 more
wiley   +1 more source

Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma

, 2007
Classification of liposarcoma into three biological types encompassing five subtypes, (a) well-differentiated/dedifferentiated, (b) myxoid/round cell, and (c) pleomorphic, based on morphologic features and cytogenetic aberrations, is widely accepted ...
Schwartz, G. K., Wu, Y., G. Ambrosini, Antonescu, C. R., C. R. Antonescu, A. Viale, Sander, C., Socci, N. D., N. D. Socci, Decarolis, P., S. Singer, E. Sambol, P. Decarolis, Y. Wu, O'Connor, R., R. Maki, Singer, S., C. Sander, Ambrosini, G., Viale, A., G. K. Schwartz, Maki, R., R. O'Connor, Sambol, E.   +23 more
core   +1 more source

Survival and prognostic factors among different types of liposarcomas based on SEER database

Scientific Reports
The aim of this study is to elucidate the disparities in survival and risk factors among different subtypes of liposarcoma, through analysis of epidemiological and prognostic data.
Jiaqi Zhao, WenLi Du, XiaoLiang Tao, AiAi Li, Yi Li, Shuai Zhang   +5 more
doaj   +1 more source

Not all NTRK fusions in mesenchymal neoplasia are driver events: implications on classification and targeted therapy

The Journal of Pathology: Clinical Research, Volume 12, Issue 5, September 2026.
Abstract NTRK fusions drive the pathogenesis of a distinctive group of mesenchymal neoplasms with significant impact on classification and targeted therapy. However, unexpected NTRK fusions have been reported in other sarcoma entities, raising uncertainty over their specificity and clinical management.
Mohamed A Yakoub, Purvil Sukhadia, Carla Saoud, Meera Hameed, Cristina R Antonescu   +4 more
wiley   +1 more source

Paratesticular well-differentiated liposarcoma initially diagnosed as fibrous pseudotumour

Indian Journal of Pathology and Microbiology, 2020
Paratesticular tumours are relatively rare and mostly of the mesenchymal origin. Due to its rarity, general surgical pathologists might have limited experience on the diagnostic entities and relevant differential diagnoses related to mesenchymal ...
Svitlana Y Bachurska, Petar A Antonov, Ivan Y Dechev, Antonio Lopez-Beltran   +3 more
doaj   +1 more source

MAGEA Family Gene Expression Influences Survival in Intestinal‐Type Gastric Cancer

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Gastric cancer (GC) is a heterogeneous disease characterized by diverse molecular profiles and distinct histological subtypes, each with differing prognoses and therapeutic responses. Melanoma‐associated antigen‐A (MAGEA) genes encode cancer testis antigens frequently expressed in tumor tissue and in limited amounts in normal tissues, making ...
Silke Neumann, Trevor Leong, Rita A. Busuttil, Alex Boussioutas, Sharon T. Pattison   +4 more
wiley   +1 more source

Systemic Therapy in Metastatic or Unresectable Well-Differentiated/Dedifferentiated Liposarcoma

, 2017
Liposarcoma is one of the most common subtypes of soft-tissue sarcoma and consists of three main subtypes, of which well-differentiated liposarcoma and dedifferentiated liposarcoma account for 40–45%.
Charlie D. Zhou, Robin L. Jones, Yevette McGovern   +2 more
core   +1 more source

A Giant Fat‐Containing Lesion of the Terminal Ileum: Imaging‐Guided Surgical Management

ANZ Journal of Surgery, EarlyView.
Eddy Traversari, Raissa De Oliveira Aquino Schuffner, Jérôme Guiramand, Jacques‐Emmanuel Saadoun   +3 more
wiley   +1 more source

Intra‐Abdominal Myxoid Leiomyosarcoma With PLAG1 Gene Rearrangement Following Prior Laparoscopic Myomectomy: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT PLAG1 immunohistochemistry and FISH were essential for diagnosis of extra‐uterine myxoid leiomyosarcoma and should be considered in myxoid intra‐abdominal tumors, especially in patients with previous uterine surgery.
Cheng‐En Hsieh, Po‐Hsuan Wu, Chang‐Wei Su, Yu‐Chun Ma, Hsuan‐Ying Huang   +4 more
wiley   +1 more source