Results 71 to 80 of about 828,080 (265)

Repeatable Switching Bridge Plug and Supporting Pressure Balance Well Completion Technology

open access: yesShiyou jixie, 2020
To address the application problem of high-density killing fluid during cased hole fracturing completion that causes reservoir damage and hinders the fracturing performance, the pressure balance well completion technology with repeatable switch bridge ...
Wang Lin   +5 more
doaj  

Study and Application of Well Completion Technique without Killing for Casing Fracturing Wells

open access: yesShiyou jixie, 2022
In view of the problems of reservoir pollution and poor fracturing results caused by high shut-in pressure in unconventional casing fracturing wells after blowout and completion operation with killing fluid and workover rigs,the well completion technique
Ping Enshun   +6 more
doaj  

Prediction model of casing annulus pressure for deepwater well drilling and completion operation

open access: yesPetroleum Exploration and Development, 2013
Casing collapse and fracture may be caused by the rise of casing annulus temperature and pressure in the initial stage of production and testing of deepwater wells.
Jin YANG   +6 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Research on key technology for efficient drilling and completion well of L-shaped horizontal well of surface mining

open access: yesMeikuang Anquan
The L-shaped horizontal shaft of surface mining is an effective technical means to realize the corner gas control in the upper corner of coal mining face.
Yuanzhi ZHANG, Yi WANG, Jing ZHANG
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

PERFECTION OF COMPOSITIONS OF BIOPOLYMER INHIBITED SOLUTIONS FOR PRODUCTIVE FORMATIONS DRILLING-IN

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2014
The efficiency of the biopolymer, mineralized sodium formiate solutions use for producing formations drilling-in is shown. The results of experimental studies of these solutions composition and the data on their physical and mechanical properties are ...
V. P. Ovchinnikov   +2 more
doaj  

Structure Design of Abrasive-Flat-Jet Nozzle for Cavity Completion of Horizontal Coalbed Methane Well

open access: yesShiyou jixie, 2021
The current hydraulic cave-making methods cannot determine the geometric size and shape of the caverns of vertical wells for coal-bed methane development, while the mechanical cavern-making method is prone to cutter bar deformation and tools falling into
Yang Ruiyue   +5 more
doaj  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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