Results 91 to 100 of about 18,677,251 (287)
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Improving well-being and efficiency in order picking
For processes that rely largely on manual activities, such as order picking, human factors need to be considered for aligning decision-making with actual system performance. This paper proposes a joint order picking batching and sequencing problem formulation with worker fatigue modeling. The fatigue level induces a decrease in performance, thus making
Giacomelli, Marco +3 more
openaire +3 more sources
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The paper presents a method for arrangement the oil and gas wells overhaul repair with attraction of service companies and proves the effectiveness of the proposed scheme of jobs organization and gives a determination of well work-over services.
A. V. Kustyshev +2 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Rebound: Efficient, Expressive, and Well-Scoped Binding
We introduce the Rebound library that supports well-scoped term representations in Haskell and automates the definition of substitution, alpha-equivalence, and other operations that work with binding structures. The key idea of our design is the use of first-class environments that map variables to expressions in some new scope.
Noé De Santo, Stephanie Weirich
openaire +3 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Business and industry e, energy, resources
Title from p. [1] of PDF (viewed Mar. 13, 2006).; "Created: 9/7/2005...; Modified 9/21/2005"--Document properties screen.; Designed to be printed on one sheet, front and back, and then folded into a pamphlet.; Harvested from the web on 3/14/06Lists low ...
Ohio. Office of Energy Efficiency.
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source

