Results 91 to 100 of about 6,879,798 (323)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
The Pricing of Short-Lived Options When Price Uncertainty Is Log-Symmetric Stable [PDF]
The well-known option pricing formula of Black and Scholes depends upon the assumption that price fluctuations are log-normal. However, this formula greatly underestimates the value of options with a low probability of being exercised if, as appears to ...
J. Huston McCulloch
core
Synthetic well logs generation via Recurrent Neural Networks
Petroleum Exploration and Development, 2018 To supplement missing logging information without increasing economic cost, a machine learning method to generate synthetic well logs from the existing log data was presented, and the experimental verification and application effect analysis were carried
Dongxiao ZHANG, Yuntian CHEN, Jin MENG
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Scientific ReportsThe exploration and development of hydrocarbon resources in the Western Desert require more continuous activities. The Silah is a newly discovered field in this region.
Mohamed Osman Ebraheem +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Research Status and Development Direction of Well Log Cyclostratigraphy
Cejing jishuWell log cyclostratigraphy has become the foundation for studying many key scientific issues in the field of geosciences by identifying, extracting, and interpreting astronomical cycles recorded by geophysical logs. This paper analyzes the driving forces
PENG Cheng, ZOU Changchun, CAO Jinyu
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
nLSALog: An Anomaly Detection Framework for Log Sequence in Security Management
IEEE Access, 2019 For the security defense in the current Intelligent Transportation System (ITS), malware is often used as the security analysis data source, but only the known attack type can be detected. A general anomaly detection framework is proposed, using log data
Ruipeng Yang +4 more
doaj +1 more source