Results 81 to 90 of about 3,299,364 (288)

Simulating elastic wave propagation in boreholes: Fundamentals of seismic response and quantitative interpretation of well log data

open access: yesGeofísica Internacional, 2011
Se presenta una formulación analítica orientada al entendimiento de la difracción, dispersión y atenuación de los modos de propagación en pozo.
Rafael Ávila-Carrera   +2 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Machine Learning-Based Prediction of Subsurface Elastic Properties Using Seismic and Well-Log Data

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The elastic properties of subsurface media, such as density and P- and S-wave velocity, are essential for understanding the mechanical behavior of the subsurface as they reflect its physical and structural characteristics. Accurate elastic properties are
Sujeong Kim   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Microscopic Origin of Non-Gaussian Distributions of Financial Returns

open access: yes, 2007
In this paper we study the possible microscopic origin of heavy-tailed probability density distributions for the price variation of financial instruments.
Black   +24 more
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Group Method of Data Handling (GMDH) Lithology Identification Based on Wavelet Analysis and Dimensionality Reduction as Well Log Data Pre-Processing Techniques

open access: yesEnergies, 2019
Although the group method of data handling (GMDH) is a self-organizing metaheuristic neural network capable of developing a classification function using influential input variables, the results can be improved by using some pre-processing steps. In this
Chuanbo Shen   +4 more
doaj   +1 more source

The evolution of HI and CIV quasar absorption line systems at 1.9 < z < 3.2

open access: yes, 2013
We have investigated the distribution and evolution of ~3100 intergalactic HI absorbers with HI column densities log N(HI) = [12.75, 17.0] at 1.9 < z < 3.2, using 18 high resolution, high S/N quasar spectra obtained from the ESO VLT/UVES archive. We used
Carswell, Robert F.   +3 more
core   +1 more source

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