Results 121 to 130 of about 355,630 (305)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Machine learning applications for well-logging interpretation of the Vikulov Formation

Georesursy
Nowadays well logging curves are interpreted by geologists who preprocess the data and normalize the curves for this purpose. The preparation process can take a long time, especially when hundreds and thousands of wells are involved.
V. I. Sakhnyuk, E. V. Novikov, A. M. Sharifullin, V. S. Belokhin, A. P. Antonov, M. U. Karpushin, M. A. Bolshakova, S. A. Afonin, R. S. Sautkin, A. A. Suslova   +9 more
doaj   +1 more source

Design of hoist drive for well logging operations [PDF]

Acta Montanistica Slovaca, 1997
Meracia sonda použitá pri karotáži, ktorá sa spúša a vyahuje na lane poèas každého meracieho cyklu konštantnou rýchlosou, neposkytuje konštantnú rýchlos hnacieho lana, spôsobujúc nepresné výsledky merania registrované na povrchu.
Bednarz Stanislaw, Zieba Anton, Furmanik Kazimierz   +2 more
doaj  

Gathering a corpus of multimodal computer-mediated meetings with focus on text and audio interaction [PDF]

, 2006
In this paper we describe the gathering of a corpus of synchronised speech and text interaction over the network. The data collection scenarios characterise audio meetings with a significant textual component.
Bouamrane, Matt-Mouley, Masoodian, Masood, Saturnion, Luz   +2 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Responses of salmonids to habitat changes [PDF]

, 1991
Streams in western North America provide spawning and rearing habitats for several species of salmon and trout that are of substantial economic importance in the region.
Bisson, P. A., Hall, James D., Hicks, Brendan J., Sedell, J. R.   +3 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The Social Banditry in the Rural Areas of Rembang by the End of the 19th Century and at the Beginning of the 20th Century [PDF]

, 2011
The social banditry is the act of crime committed by the residents of a village or the people in the low economic and social stratum in order to fulfill their basic needs.
Warto,
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source