Results 71 to 80 of about 358,289 (299)

Solomon Island Nongovernment Organizations: Major Environmental Actors [PDF]

open access: yes, 1997
The scattered nature of Solomon Island villages, the people’s low literacy rate, and the country’s many languages make it difficult to share development and environment messages effectively. Solomon Islands Development Trust has had a fourteen-year track
Roughan, John
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Is community forest-based enterprises sustainable in Amazon? [PDF]

open access: yes, 2009
Since the end of the 1990s, the Brazilian PROMANEJO program (Projeto de Apoio ao Manejo Florestal Sustentável na Amazônia) financed several community forest-based enterprises (CFEs). CFEs are seen as an opportunity for extractivist and farmers interested
Abramovay, Ricardo   +3 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The Tropical managed Forests Observatory: a research network addressing the future of tropical logged forests [PDF]

open access: yes, 2019
While attention to logging in the tropics has been increasing, studies on the long-term effects of silviculture on forest dynamics and ecology remain scare and spatially limited.
Sist, Plinio
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A novel productivity evaluation approach based on the morphological analysis and fuzzy mathematics: insights from the tight sandstone gas reservoir in the Ordos Basin, China

open access: yesJournal of Petroleum Exploration and Production Technology, 2019
Tight gas reservoirs have rich potential resources, which are hot spots in unconventional oil and gas exploration and development. Due to their strong heterogeneity and complex pore structures, the conventional approaches of productivity evaluation ...
Shanyong Liu   +4 more
doaj   +1 more source

SMILE: the creation of space for interaction through blended digital technology [PDF]

open access: yes, 2003
Interactive Learning Environments at Sussex University is a course in which students are given mobile devices (XDAs) with PDA functionality and full Internet access for the duration of the term.
Brewster, Diane   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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