Results 101 to 110 of about 468,437 (298)

Semantic Support for Log Analysis of Safety-Critical Embedded Systems

open access: yes, 2014
Testing is a relevant activity for the development life-cycle of Safety Critical Embedded systems. In particular, much effort is spent for analysis and classification of test logs from SCADA subsystems, especially when failures occur. The human expertise
Ficco, Massimo   +3 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Correlation of Boreholes through Well Logs: Application to the Western Sector of Madrid. [PDF]

open access: yesSensors (Basel), 2023
Díaz-Curiel J   +4 more
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Predictive pore pressure modeling using well-log data in the West Baram Delta, offshore Sarawak Basin, Malaysia

open access: yesGeomechanics and Geophysics for Geo-Energy and Geo-Resources
Accurate prediction of pore pressure (PP) is crucial for optimizing drilling and reservoir management operations. This study investigates PP prediction in the West Baram Delta, Offshore Sarawak, a mature oil and gas field.
Dejen Teklu Asfha   +3 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Characterization of the Structural–Stratigraphic and Reservoir Controls on the Occurrence of Gas Hydrates in the Eileen Gas Hydrate Trend, Alaska North Slope

open access: yesJournal of Marine Science and Engineering
One of the most studied permafrost-associated gas hydrate accumulations in Arctic Alaska is the Eileen Gas Hydrate Trend. This study provides a detailed re-examination of the Eileen Gas Hydrate Trend with a focus on the gas hydrate accumulation in the ...
Margarita Zyrianova   +2 more
doaj   +1 more source

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