Results 131 to 140 of about 481,493 (348)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Energy Production Potential of Ultra-Deep Reservoirs in Keshen Gas Field, Tarim Basin: From the Perspective of Prediction of Effective Reservoir Rocks

Energies
The identification and prediction of effective reservoir rocks are important for evaluating the energy production potential of ultra-deep tight sandstone reservoirs.
Zhida Liu, Xianqiang Song, Xiaofei Fu, Xiaorong Luo, Haixue Wang   +4 more
doaj   +1 more source

DSDP Leg 65, Hole 482C - Well Logging Data

, 2020
Brian T. R. Lewis, Paul T. Robinson, R.N. Benson, Grant Blackinton, Pierre Cambon, Ron Day, Frederick K. Duennebier, Martin F. J. Flower, Mario Gutiérrez-Estrada, John G. Hattner, Albert M. Kudo, M. A. Morrison, Claude Rangin, Matthew H. Salisbury, Hans‐Ulrich Schmincke, Ralph A. Stephen, Boris P. Zolotarev   +16 more
openalex   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Application of Magnetic Tapes to Well Logging [PDF]

, 1966
D.H. Tinch, Greg Miller, B.N. Carpenter, J.P. Warren   +3 more
openalex   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

IODP Expedition 336, Hole U1382A - Well Logging Data

, 2021
Katrina J. Edwards, Wolfgang Bach, Adam Klaus, Louise Anderson, Nicolas Backert, Keir Becker, Jean-Paul Baquiran, Dale W. Griffin, Amanda G. Haddad, Yumiko Harigane, Hisako Hirayama, Samuel M. Hulme, Steffen Leth Joergensen, Tania Lado Insua, Paul Le Campion, Heath J. Mills, Kentaro Nakamura, Beth N. Orcutt, Young-Soo Park, Victoria Rennie, Olivier Rouxel, Joseph A. Russel, Kasumi Sakata, Everett C. Salas, Fengping Wang, C.G. Wheat   +25 more
openalex   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source