Results 41 to 50 of about 235,878 (262)

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Perceived Physical Activity Levels and Objective Measures: A Mixed-Methods Study of Residents Aged 65 and Above in Assisted Living Homes in Australia

Journal of Aging Research
Conclusion: This study provides valuable insight into the demographic and health factors contributing to higher levels of activity, and the perceptions of activity among older adults vulnerable to health conditions associated with inactivity.
Samaher Alowaydhah, Ishanka Weerasekara, Sarah Walmsley, Sally Keir, Jodie Marquez   +4 more
doaj   +1 more source

Population-based cancer incidence and mortality rates and ratios among adults with intellectual disabilities in Scotland: a retrospective cohort study with record linkage

BMJ Open
Objective To provide contemporary data on cancer mortality rates within the context of incidence in the population with intellectual disabilities.Methods Scotland’s 2011 Census was used to identify adults with intellectual disabilities and controls with ...
Angela Henderson, Sally-Ann Cooper, Kirsty Dunn, Colin McCowan, Michael Fleming, David Morrison, David Conway, Gill Smith, Maria Truesdale, Filip Sosenko, Deborah Cairns, Laura Hughes-McCormack, Katie Robb, Laura McKernan Ward, Catherine R Hanna   +14 more
doaj   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

The acceptability of a novel seismocardiography device for measuring VO2 max in a workplace setting: a mixed methods approach

BMC Public Health
Background Workplace health screening rarely includes measures of cardiorespiratory fitness, despite it being a greater predictor of cardiovascular disease and all-cause mortality than other routinely measured risk factors.
Anouska M Carter, Liam Humphreys, Alison Beswick, Sue Kesterton, Alex Bugg, Katharine Platts   +5 more
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

An observational analysis of frailty in combination with loneliness or social isolation and their association with socioeconomic deprivation, hospitalisation and mortality among UK Biobank participants

Scientific Reports
Frailty, social isolation, and loneliness have individually been associated with adverse health outcomes. This study examines how frailty in combination with loneliness or social isolation is associated with socioeconomic deprivation and with all-cause ...
Marina Politis, Lynsay Crawford, Bhautesh D. Jani, Barbara I. Nicholl, Jim Lewsey, David A. McAllister, Frances S. Mair, Peter Hanlon   +7 more
doaj   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source

The Sensitivity of Wellbeing to Inequalities in Local Wellbeing [PDF]

, 2021
<p>Research points to a robust negative relationship between average levels of subjective wellbeing and the distribution of subjective wellbeing. The fact that our wellbeing falls as wellbeing distributions widen suggests we care about inequalities in the lives of others.
openaire   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source