Results 101 to 110 of about 151,746 (314)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
SPECIAL SERIES: FINANCIAL WELLNESS WEBSITES IN HIGHER EDUCATION
Although institutions of higher education in the United States have published websites since the late 1990s, little is known regarding whether institutions publish financial wellness-related content on their websites and specifically where this ...
Mesa, Joseph +15 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
UNO Website Wellness Center Guidebook
The Wellness Center encourages you to balance your life by making beneficial choices and becoming more aware of your overall wholeness, happiness, and ...
Wellness Center, UNO
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Analysis of the wellness hotels
Szakdolgozatom a wellness szállodák több szempontból való elemzéséről szól. Elemzési szempontok a demográfiai szempontok alapján, a szállodák weboldala szempontjából, a szálláskínáló oldalak szempontjából, vendégelégedettség alapján és földrajzi fekvésük
Kerekes, Regina
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Problem Statement: University surveys revealed increased stress and burnout among nursing academia faculty and staff. Goal/Aim: The goal of this project was to determine whether integrating wellness initiatives would lead to reduced stress and burnout ...
Cheryl Armstrong; Jennifer Macali; Sara Simonsen; Katarina Felsted; Jennifer Clifton
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