Results 141 to 150 of about 151,746 (314)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Nursing Procedures for the Patient Submitted to Cardiac Catheterism - Scientific Production Analysis
Facing the importance of existing parameters for the nursing care systematization to the patients submitted to cardiac catheterism, the necessity of availability of scientific studies related to the subject is clear in order to present the establishment ...
Rosane Brinques Lourenci
doaj
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Knowing Well, Being Well: well-being born of understanding [PDF]
Sara S, Johnson +3 more
openaire +5 more sources
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Wellness-tourism in the Northern Great Plain Region
A szakdolgozatomban az egészségturizmus egyik legdinamikusabban fejlődő ágát vizsgálom: a wellness-turizmust. Az Észak-Alföld egy olyan régió Magyarországon, amely az egyik leggazdagabb természetes erőforrásokban, így az ország több pontjáról, ezen ...
Meszesán, Henrietta
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

