Results 141 to 150 of about 151,746 (314)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Nursing Procedures for the Patient Submitted to Cardiac Catheterism - Scientific Production Analysis

open access: yesOnline Brazilian Journal of Nursing, 2006
Facing the importance of existing parameters for the nursing care systematization to the patients submitted to cardiac catheterism, the necessity of availability of scientific studies related to the subject is clear in order to present the establishment ...
Rosane Brinques Lourenci
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Knowing Well, Being Well: well-being born of understanding [PDF]

open access: yesAmerican Journal of Health Promotion, 2020
Sara S, Johnson   +3 more
openaire   +5 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Transcranial Magnetic Stimulation Outcomes by Age: A Retrospective Chart Review in a Naturalistic Clinic Setting

open access: yesBrain Stimulation, 2021
Phillip Goldman   +3 more
doaj   +1 more source

Wellness-tourism in the Northern Great Plain Region

open access: yes
A szakdolgozatomban az egészségturizmus egyik legdinamikusabban fejlődő ágát vizsgálom: a wellness-turizmust. Az Észak-Alföld egy olyan régió Magyarországon, amely az egyik leggazdagabb természetes erőforrásokban, így az ország több pontjáról, ezen ...
Meszesán, Henrietta
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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