Results 11 to 20 of about 1,154,769 (315)

Lin−CCR2+ hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade

Nature Communications, 2018
Brain tumors are difficult to treat using existing immunotherapeutic strategies. Here, the authors show that in brain tumors resistant to PD-1 blockade, HSCs expressing CCR2+ can reverse treatment resistance and sensitizes mice to immunotherapy.
Catherine T. Flores, Tyler J. Wildes, Jeffrey A. Drake, Ginger L. Moore, Bayli DiVita Dean, Rebecca S. Abraham, Duane A. Mitchell   +6 more
doaj   +1 more source

Combined Well Multi-Parameter Logs and Low-Flow Purging Data for Soil Permeability Assessment and Related Effects on Groundwater Sampling

Hydrology, 2023
Cost-effective remediation is increasingly dependent on high-resolution site characterization (HRSC), which is supposed to be necessary prior to interventions.
Francesco Maria De Filippi, Giuseppe Sappa   +1 more
doaj   +1 more source

Emerging trends in immunotherapy for pediatric sarcomas

Journal of Hematology & Oncology, 2019
While promising, immunotherapy has yet to be fully unlocked for the preponderance of cancers where conventional chemoradiation reigns. This remains particularly evident in pediatric sarcomas where standard of care has not appreciably changed in decades ...
Kyle A. Dyson, Brian D. Stover, Adam Grippin, Hector R. Mendez-Gomez, Joanne Lagmay, Duane A. Mitchell, Elias J. Sayour   +6 more
doaj   +1 more source

All’s Well That Scales Well [PDF]

Cell Systems, 2016
An unexpected thread ties together a few of the articles in this issue of Cell Systems.Our cover article introduces the ontotype (Yu et al., pp. 77–88). Akin to genotype and phenotype, an individual’s genetic and physical characteristics, an ontotype is the genotype organized and aggregated using a gene ontology.
openaire   +2 more sources

Determination The Suitable Locations for Drilling Wells for Irrigation purpose by using Geographic Information System (GIS [PDF]

Engineering and Technology Journal, 2016
This study was conducted for the purpose of study and analysis of groundwater in the Karbala Governorate. Relied on a set of data and maps that relate to groundwater, topography and geology of the region in addition to 60 wells were distributed randomly ...
Alaa Ghadhban Khalaf
doaj   +1 more source

Primary thoracic spine amyloidoma causing malignant cord compression: A case report and review of the literature

The Royal College of Radiologists Open
Purpose: Amyloidoma is a rare pseudo-tumoral form of localised amyloidosis. This condition is thought to rarely affect the spine, with less than 100 cases of spinal amyloidomas described in literature and their properties are not well understood ...
O. Olujobi, A. Gough-Palmer, A. Shaw
doaj   +1 more source

CXCR1- or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors

Nature Communications, 2019
CAR T-cell therapy efficacy in solid tumors is limited by inadequate T-cell migration and/or persistence in tumour microenvironment. Here, the authors show that the activity of tumour-antigen specific CAR T cells, in multiple preclinical mouse models ...
Linchun Jin, Haipeng Tao, Aida Karachi, Yu Long, Alicia Y. Hou, Meng Na, Kyle A. Dyson, Adam J. Grippin, Loic P. Deleyrolle, Wang Zhang, Didier A. Rajon, Qiong J. Wang, James C. Yang, Jesse L. Kresak, Elias J. Sayour, Maryam Rahman, Frank J. Bova, Zhiguo Lin, Duane A. Mitchell, Jianping Huang   +19 more
doaj   +1 more source

Review of Literary Bioethics: Animality, Disability, and the Human by Maren Tova Linett

Disability Studies Quarterly, 2021
No abstract available.
D. Christopher Gabbard
doaj   +1 more source

On Writing Well…and Not So Well

Ubiquity, 2023
Each "Communication Corner" essay is self-contained; however, they build on each other. For best results, before reading this essay and doing the exercise, go to the first essay "How an Ugly Duckling Became a Swan," then read each succeeding essay. Books on good writing are virtually ubiquitous.
openaire   +1 more source

Building relational well-being: empowering street-connected young people to transition from precarity to security through youth associations

BMJ Paediatrics Open
Street-connected young people (SCYP) in Tanzania face intersecting challenges, including economic vulnerability, social marginalisation and limited access to supportive networks.
Kate McAlpine, Isabel Cooper, Raphael Dennis   +2 more
doaj   +1 more source