Comparison of the detection of the chronic wasting disease prion by real-time quaking-induced conversion (rtQuIC) and silica nanoparticle-rtQuIC (nano-rtQuIC) assays in retropharyngeal lymph nodes of white-tailed deer, mule deer, and Rocky Mountain elk. [PDF]
Ralston BA, Jennings J, Allen SE.
europepmc +1 more source
Sleep Well, Eat Well, and Live Well
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
A 3D model to evaluate cell chemotaxis within a heterogenic tumor microenvironment.
Rodrigues DB +6 more
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Research and application of quantitative model for optimal well trajectory selection. [PDF]
Xiao Y +6 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Teaching Aquitard Concepts With Field-Based High-Resolution Head Profile Learning Activities. [PDF]
Meyer JR, Tassier-Surine S, Cramer B.
europepmc +1 more source
A Common Ancestry-Specific Sodium Channel Variant Increases Susceptibility to Drug-Induced QTc Prolongation: Evidence From a Large Biobank. [PDF]
Stewart R +6 more
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AMP-activated protein kinase-driven lipid droplet dynamics govern melanoma sensitivity to polyunsaturated fatty acid and iron-induced ferroptosis. [PDF]
Motamedi S +11 more
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