Results 121 to 130 of about 436,672 (299)

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

open access: yesAdvanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li   +9 more
wiley   +1 more source

Review of the school workload advisory panel: final report [PDF]

open access: yes, 2009
The School Workload Advisory Panel (SWAP) was established as an independent body in 2004 by the Welsh Assembly Government with a remit that was aimed at reducing bureaucratic burdens on schools.

core  

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

open access: yesAdvanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno   +16 more
wiley   +1 more source

An HEI-disaggregated input-output table for Wales [PDF]

open access: yes, 2010
This paper describes how the education sector of the Welsh Input-Output tables is disaggregated to identify a separate sector for each of Wales’s twelve Higher Education Institutions (HEIs).
Hermannsson, Kristinn   +3 more
core   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

open access: yesAdvanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad   +6 more
wiley   +1 more source

Surname studies with genetics [PDF]

open access: yes, 2009
Genetic studies of surnames are briefly reviewed. In particular, such DNA studies can sometimes provide clues to a surname's meaning. A few surnames are being found to include unusually large single families, which are far more populous than computer ...
Plant, Dr John S
core  

Direct Synthesis of High‐Valence Protein@UiO‐66 Composites: Linking Crystallization Pathways to Protein Encapsulation

open access: yesAdvanced Materials, EarlyView.
This work reports a direct, biocompatible method to synthesize UiO‐66, enabling one‐step encapsulation of proteins without compromising crystallinity or activity. Using advanced in situ and ex situ techniques, the study reveals that proteins integrate concurrently with MOF growth, forming crystalline protein@UiO‐66 nanoparticles, and provide insight ...
Jesús Cases Díaz   +5 more
wiley   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Foundation Phase training and its impact on learning and teaching: an interim report [PDF]

open access: yes, 2010
"This report has been written in response to the annual Ministerial remit letter from the Welsh Assembly Government, which requested information about how well the National Training Programme for practitioners in the Foundation Phase is being implemented

core  

Navigating the meso-level bottleneck: Language rights implementation in Welsh healthcare

open access: yesRevista de Llengua i Dret - Journal of Language and Law
Language is a key factor in the delivery of effective healthcare, especially in settings where service users speak a minoritised language. In Wales, the Welsh Government has acknowledged the importance of linguistic inclusion through initiatives such as
Cynog Prys, Rhian Hodges
doaj   +1 more source

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