Results 121 to 130 of about 54,241 (248)

Assessment of postoperative range of motion in paediatric patients undergoing surgical reduction and fixation of lateral condyle fractures. [PDF]

J Child Orthop
Rehm A, Liew I, Welsh K, Barwell J, Stohlner V, Ashby E.   +5 more
europepmc   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

Advanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang, Zhehao Lin, Lu Chen, Ying Ni, Jun Zhou, Wenjuan Zhang, Huilin Wang, Peifeng Ying, Xiu Lu, Kai Wang, Qingran Kong, Naxin Xu, Dingsheng Zhao, Jianwei Li, Guohui Zhong, Xingchen Meng, Sarkawt Hamad, Junmeng Zheng, Yuan Fu, Rongjiang Qin, Xuran Chu, Shangxuan Li, Youyou Li, Yili Wu, Yi Wang, Weihong Song, Yingxian Li, Shukuan Ling   +27 more
wiley   +1 more source

Usability testing of a digital tool to support behavioural activation for depression with young people aged 12 to 18. [PDF]

Front Child Adolesc Psychiatry
Tindall L, Kerrigan P, Standley E, Metcalfe S, O'Brien M, Gega L.   +5 more
europepmc   +1 more source

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

Advanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang, Shuhan Duan, Qiuxia Sun, Renkuan Tang, Lintao Luo, Jie Zhong, Zhaxylyk Sabitov, CAGDP Consortium†, Lan‐Hai Wei, Chao Liu, Maxat Zhabagin, Guanglin He   +11 more
wiley   +1 more source

Historical Writing in Medieval Welsh

Scottish Studies, 1968
Thomas Jones
doaj  

Concerns Regarding the Efficacy of Utilizing the Vibrational Response of Aminocyanine Molecules to Near Infrared Light for Cancer Cell Destruction. [PDF]

J Biomed Phys Eng
Faghani-Eskandarkolaei P, Welsh J, Mortazavi SAR, Taghizadeh P, Baramaki M, Shams F, Abubakari MN, Mortazavi SMJ, Sihver L.   +8 more
europepmc   +1 more source

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

Advanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong, Wenlong Chen, Fanglong Liu, Shengyi Zhou, Bolin Yu, Yuying Wang, Xiqian Zhou, Xuehui Wang, Diya Liu, Zhuoyu Zhang, Xinran Wang, Mounia Lalouly, Yiwen Li, Zhefei Du, Tao Yan, Zhihui Xiao, Zhou Zhou, Huanhuan Zhu, Fengyuan Qian, Bowen Zheng, Lin Fang   +20 more
wiley   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

Indo-European and Celtic

Scottish Studies, 1968
Wolfgang Meid
doaj  

Heparanase inhibition prevents glycocalyx damage and albuminuria in experimental minimal change disease. [PDF]

Clin Transl Med
Crompton M, Ramnath RD, Betteridge K, Desideri S, Alonso AM, Jiang L, Gamez M, Stowell-Connolly H, Vasylchenko V, Onions KL, Butler MJ, Neal CR, Salmon AHJ, Turnbull JE, Kawachi H, Zubkova OV, Welsh GI, Satchell SC, Foster RR.   +18 more
europepmc   +1 more source