Results 31 to 40 of about 157,919 (310)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Does the transparency of the counting system affect children's numerical abilities?

open access: yesFrontiers in Psychology, 2015
The Welsh language uses a regular counting system, whereas English uses an irregular counting system, and schools within Wales teach either through the medium of Welsh or English.
Ann eDowker, Manon eRoberts
doaj   +1 more source

Welsh Language Fanfiction in Light of Welsh Cultural and National Identity and Language Revitalisation

open access: yesStudia Celtica Posnaniensia, 2023
While the field of fan studies is constantly growing, it has been scarcely researched in relation to minority languages and language revitalisation. In this paper we have undertaken to explore the small and previously unexplored realm of Welsh-language fanfiction, focusing on the motivations to read and write it.
Nikola Zduńczyk   +2 more
openaire   +1 more source

Good practice guide for sector and standard setting bodies (guidance) [PDF]

open access: yes, 2010
"This guide is for sector and standards setting bodies to assist them in determining the demand for Welsh language skills, Welsh translations of national occupational standards (NOS) and vocational qualifications (VQs) through the medium of Welsh ...

core  

Formal and informal social care in people with Rheumatic and Musculoskeletal diseases: a cross‐sectional multicentre survey

open access: yesArthritis Care &Research, Accepted Article.
Introduction Rheumatic and musculoskeletal diseases(RMDs) are leading causes of physical disability, necessitating support with activities of daily living(ADLs). This study describes social care received by patients with RMDs in two disperate regions of England: Salford(urban) and Norfolk(rural).
Mehreen Somro   +6 more
wiley   +1 more source

Bio‐Orthogonally Crosslinked Supramolecular Polymer Bottlebrush Hydrogels for Long‐Term 3D Cell Culture

open access: yesAdvanced Functional Materials, EarlyView.
Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi   +5 more
wiley   +1 more source

Electrophysiological Differentiation of the Effects of Stress and Accent on Lexical Integration in Highly Fluent Bilinguals

open access: yesBrain Sciences, 2020
Individuals who acquire a second language (L2) after infancy often retain features of their native language (L1) accent. Cross-language priming studies have shown negative effects of L1 accent on L2 comprehension, but the role of specific speech features,
Jennifer Lewendon   +2 more
doaj   +1 more source

Welsh-medium education strategy : annual report 2010–11 [PDF]

open access: yes, 2011
"The Welsh-medium Education Strategy was published by the Welsh Government in April 2010 in fulfilment of a One Wales commitment to ‘create a national Welsh-medium Education Strategy to develop effective provision from nursery through to further and ...

core  

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

open access: yesAdvanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin   +14 more
wiley   +1 more source

Mobile Informal Language Learning: Exploring Welsh Learners’ Practices [PDF]

open access: yes, 2015
Mobile devices have great potential in supporting language learning, through providing access to vocabulary, lessons and resources, and supporting interactions with other speakers.
Jones, Ann
core  

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