Results 81 to 90 of about 114,643 (250)
Structure‐based discovery of thiamine uptake inhibitors
British Journal of Pharmacology, Volume 182, Issue 22, Page 5611-5626, November 2025.Background and Purpose Thiamine (vitamin B1) is an essential coenzyme and catalyses various reactions in central metabolic pathways. Since mammals have lost the ability to synthesise thiamine de novo, this micronutrient has to be imported via the high affinity solute carriers SLC19A2 and A3 across the plasma membrane.
Florian Gabriel +2 more
wiley +1 more source
Wernicke\u27s Encephalopathy: Mapping the Risk Factors Throughout the State of South Carolina [PDF]
, 2023 Wernicke’s Encephalopathy is a consistently underrecognized neurodegenerative brain disorder resulting from prolonged thiamine deficiency. Clinical presentation of the disease results from brain lesions attributable to thiamine deficiency.
Rychener, Shannon M
core +1 more source
MULTIPLE CEREBRAL METASTASES MIMICKING WERNICKE'S ENCEPHALOPATHY IN A CHRONIC ALCOHOLIC [PDF]
, 2017 Aims: Alcohol dependent patients in withdrawal display a wide spectrum of neurological and neuropsychological symptoms that complicate diagnosis. We report the case of a 53-year-old male alcoholic with disorientation, ataxia and nystagmus in alcohol ...
EULER, SEBASTIAN +4 more
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Mammillothalamic functional connectivity and memory function in Wernicke's encephalopathy [PDF]
, 2009 There is still debate over the neural mechanisms underlying pathogenic and even recovery processes of Wernicke's encephalopathy. Therefore, we attempted to validate the usefulness of resting-state functional connectivity analysis in assessing memory ...
김어수 +5 more
core +1 more source
From Treatment to Toxicity: Metronidazole‐Induced Encephalopathy in a 79‐Year‐Old Woman
Clinical Case Reports, Volume 13, Issue 10, October 2025.ABSTRACT Metronidazole is a commonly used antibiotic effective against anaerobic bacterial and protozoal infections. While generally well tolerated, it is associated with potential neurotoxic effects, including metronidazole‐induced encephalopathy (MIE), especially in elderly patients or those with hepatic impairment.
Minoo Heidari Almasi +4 more
wiley +1 more source
A Historical Approach to Alcohol Abuse [PDF]
, 2013 Alcohol consuming is so present in human history to the extent that it has become ‘a universal language’. Under this point of view, studying historical trends regarding alcohol consume, geographical profile of its abuse, political approaches at the level
Nikaj, Afërdita, Vyshka, Gentian
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Wernicke Encephalopathy Presenting in a Patient with Severe Acute Pancreatitis [PDF]
, 2012 Context Acute pancreatitis can lead to prolonged fasting and malnutrition. Many metabolic changes, including thiamine deficiency, may lead to the well know pancreatic encephalopathy.
Arana-Guajardo, Ana Cecilia +5 more
core +2 more sources
Health Science Reports, Volume 8, Issue 10, October 2025.ABSTRACT Background and Aims Excessive alcohol consumption is a critical yet under‐researched public health problem in Angola, particularly among young adults. Although per capita consumption is among the highest in Africa, little is known about the specific neuroanatomical and psychosocial consequences in this group.
Bevaldo de Oliveira Guerra +2 more
wiley +1 more source
Food for thought : palatable eponyms from Pediatrics [PDF]
, 2014 Food-related medical terms are frequently used in the field of pediatrics for the definition, recognition and diagnosis of disease. Almost 40 food-related medical eponyms used in Pediatrics have been ‘cherry picked’ and described by the authors.
Kipersztok, Lisa, Masukume, Gwinyai
core
, 2005 BACKGROUND/AIMS: Mild hypothermia has proven useful in the clinical management of patients with acute liver failure. Acute liver failure in experimental animals results in alterations in the expression of genes coding for astrocytic proteins including ...
Butterworth, Roger +4 more
core +1 more source