Episignature-based modelled first-tier diagnostic approach in the Dutch Caribbean: advancing equal care through epigenetic classification. [PDF]
van der Laan L +15 more
europepmc +1 more source
Effects of genotype and environment on the physiochemical properties of Canadian oat varieties
Abstract BACKGROUND The relationship between oat grain composition and physical attributes as influenced by oat genotype and Canadian growing environments was investigated. Thirty Canadian oat (Avena sativa L.) genotypes, grown in three Canadian growing locations (Brandon, Manitoba; Portage la Prairie, Manitoba; and Lacombe, Alberta) over 2 consecutive
Vanessa Alexander +4 more
wiley +1 more source
ABSTRACT Sarcomas represent a diverse group of mesenchymal tumors with high rates of recurrence after resection. While recent technical advances have enabled the detection of rare circulating tumor DNA (ctDNA) in other malignancies, the complexity and heterogeneity of sarcoma genomics have historically limited ctDNA in these cancers.
Kristin E. Goodsell +5 more
wiley +1 more source
Whole-exome sequencing increases variant detection compared to karyotyping and CMA in an unselected FGR cohort. [PDF]
Liu J +6 more
europepmc +1 more source
Lonely and Sick: The Role of Social Media in Consumer Practices of Relief
ABSTRACT Loneliness is increasingly recognized as a major mental health concern, yet the role of social media in alleviating it remains poorly understood. This study asks how social media help consumers cope with loneliness amid chronic illness. Focusing on women living with endometriosis, an under‐recognized and often stigmatized condition marked by ...
Beatrice Medici +2 more
wiley +1 more source
LySeqST: a targeted sequencing assay for robust genomic classification of diffuse large B-cell lymphoma. [PDF]
Hilton LK +23 more
europepmc +1 more source
Multiomics Insights Into AL Amyloidosis
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang +6 more
wiley +1 more source
Lactational Western-Style Fat Exposure in Mice Programs Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Male Offspring. [PDF]
Zhao AY +5 more
europepmc +1 more source
FXTAS and the Spectrum of FMR1 Premutation‐Associated Phenotypes in Latin America: A Scoping Review
Abstract Background Fragile X–associated tremor/ataxia syndrome (FXTAS) is a late‐onset neurodegenerative disorder caused by FMR1 premutation expansions (55–200 CGG repeats). Although well described in populations of predominantly European ancestry, FXTAS remains poorly characterized in Latin America due to limited awareness, restricted access to ...
Amy Schmidmajer +6 more
wiley +1 more source

