Results 21 to 30 of about 28,995 (135)

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, Volume 19, Issue 10, Page 2797-2821, October 2025.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Rescue, rehabilitation, and release of marine mammals: An analysis of current views and practices. [PDF]

, 1996
Stranded marine mammals have long attracted public attention. Those that wash up dead are, for all their value to science, seldom seen by the public as more than curiosities.
Geraci, Joseph R., Lounsbury, Valerie J., St. Aubin, David J.   +2 more
core  

A New Approach to Data‐Model Comparisons: Using MAGE and Lompe to Unravel Ionosphere‐Magnetosphere Electrodynamics

Journal of Geophysical Research: Space Physics, Volume 130, Issue 10, October 2025.
Abstract Global numerical simulations are valuable tools for understanding the Sun‐Earth interaction as they provide a more thorough picture of the system when compared to typically sparse observations. Yet, comparisons of these global models against observations is complicated by the inherent uncertainty that the observed phenomena occurred at the ...
S. Gasparini, L. Kepko, K. A. Sorathia, A. Michael, V. G. Merkin, K. M. Laundal, C. Norgren   +6 more
wiley   +1 more source

Chronic Cellular NAD Depletion Activates a Viral Infection‐Like Interferon Response Through Mitochondrial DNA Leakage

Aging Cell, Volume 24, Issue 9, September 2025.
Chronic NAD depletion in fibroblasts lowers NAD levels, increases mitochondrial mass, and triggers an interferon‐dependent inflammatory response via mtDNA leakage through VDAC1, activating the cGAS‐STING pathway. This links NAD deficiency to metabolic and inflammatory processes, with implications for diseases associated with NAD decline.
Claudia C. S. Chini, Laura Colman, Eduardo Palmieri, Jessica L. Strange, Sonu Kashyap, Bing Han, Andres Benitez‐Rosendo, Gina L. Ciccio Lopez, Sara Peixoto Rabelo, Shreyartha Mukherjee, Gustavo H. de Souza, John Varga, Ralph G. Meyer, Mirella L. Meyer‐Ficca, Eduardo N. Chini   +14 more
wiley   +1 more source

216 Jewish Hospital of St. Louis [PDF]

, 1960
https://digitalcommons.wustl.edu/bjc_216/1046/thumbnail ...

core   +1 more source

The Association Between Accelerated Biological Aging and the Physical, Psychological, and Cognitive Multimorbidity and Life Expectancy: Cohort Study

Aging Cell, Volume 24, Issue 9, September 2025.
Accelerated biological aging (KDM‐BA/PhenoAge) predicts higher multimorbidity risks and 5.3–7.0 life‐years lost in 332,012 UK adults. Those with accelerated aging face 12%–37% increased transition risks to severe health states. Integrating these metrics enables targeted interventions to reduce chronic disease burdens in aging populations.
Zuliyaer Talifu, Ziyang Ren, Chen Chen, Shuai Guo, Yu Wu, Yuling Li, Binbin Su, Xiaoying Zheng   +7 more
wiley   +1 more source

Spartan Daily, February 21, 1940 [PDF]

, 1940
Volume 28, Issue 92https://scholarworks.sjsu.edu/spartandaily/3039/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

Full‐Depth Reconstruction of Long‐Term Meridional Overturning Circulation Variability From Satellite‐Measurable Quantities via Machine Learning

Journal of Advances in Modeling Earth Systems, Volume 17, Issue 7, July 2025.
Abstract The meridional overturning circulation (MOC) plays a crucial role in the global distribution of heat, carbon, and other climate‐relevant tracers. Monitoring the evolution of MOC is essential for understanding climate variability, yet direct MOC observations are sparse and geographically limited.
Huaiyu Wei, Kaushik Srinivasan, Andrew L. Stewart, Aviv Solodoch, Georgy E. Manucharyan, Andrew McC. Hogg   +5 more
wiley   +1 more source

The New Hampshire, Vol. 106, No. 45 (Apr. 20, 2017) [PDF]

, 2017
An independant student produced newspaper from the University of New ...
The New Hampshire
core   +1 more source

Economies of scope in artists' incubator projects. [PDF]

J Cult Econ (Dordr), 2021
Whitaker A.
europepmc   +1 more source