Results 31 to 40 of about 3,297,657 (222)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Trends in Women’s Educational Advantage and Divorce in East and West Germany

open access: yesComparative Population Studies
Couples in which wives have more education than their husbands have been found to be more likely than other couples to divorce. But this relationship varies across time and place.
Flavia Mazzeo   +3 more
doaj   +1 more source

Guerrilla Mothers and Distant Doubles. West German Feminists Look at China and Vietnam, 1968–1982

open access: yesZeithistorische Forschungen, 2015
Communist China and Vietnam looked like the future to many West German feminists in the years after 1968. This article reconstructs a lost history of influence, identification and emulation, tracing some of the ways that Chinese and Vietnamese communism ...
Quinn Slobodian
doaj   +1 more source

It Is Not All Because of Socialism — On East-West Differences and Their Origins

open access: yesWirtschaftsdienst, 2021
Even on the 30th anniversary of German unity, there is still a lot of talk about East-West differences. Typically, these differences are attributed to different political systems, which have created different impressions.
Sascha O. Becker   +2 more
doaj   +1 more source

Economic and Political Reconstruction and Development of FRG in the Period after World War II

open access: yesHistoria i Polityka, 2021
In the first post-war years, the policy of the Western occupying powers towards Germany was aimed at preventing the economic revival of their former formidable competitor.
Mariusz Janik
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Changes in Birth Seasonality in East and West Germany, 1946-2017

open access: yesComparative Population Studies
Seasonal trends in fertility are found in several contexts and are affected by societal and environmental factors. This paper documents how birth seasonality in East and West Germany changed over time and, in particular, after 1989 and the onset of ...
Risto Conte Keivabu
doaj   +1 more source

Die geistig-kulturelle Lage im wieder-vereinigten Deutschland

open access: yesLiterator, 1997
The mental-cultural situation of the re-united Germany In 1993 an exhibition presenting phenomena about the past, present and future of both East and West Germany took place in Berlin.
A. M. Rauch
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

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