Results 31 to 40 of about 272,608 (290)

How divisions between East and West Germany persist 30 years after reunification [PDF]

open access: yes, 2019
This article is republished from The Conversation under a Creative Commons license. Read the original at https://theconversation.com/how-divisions-between-east-and-west-germany-persist-30-years-after-reunification ...
Dale, G
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

It Is Not All Because of Socialism — On East-West Differences and Their Origins

open access: yesWirtschaftsdienst, 2021
Even on the 30th anniversary of German unity, there is still a lot of talk about East-West differences. Typically, these differences are attributed to different political systems, which have created different impressions.
Sascha O. Becker   +2 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Guerrilla Mothers and Distant Doubles. West German Feminists Look at China and Vietnam, 1968–1982

open access: yesZeithistorische Forschungen, 2015
Communist China and Vietnam looked like the future to many West German feminists in the years after 1968. This article reconstructs a lost history of influence, identification and emulation, tracing some of the ways that Chinese and Vietnamese communism ...
Quinn Slobodian
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Trends in Women’s Educational Advantage and Divorce in East and West Germany

open access: yesComparative Population Studies
Couples in which wives have more education than their husbands have been found to be more likely than other couples to divorce. But this relationship varies across time and place.
Flavia Mazzeo   +3 more
doaj   +1 more source

Die geistig-kulturelle Lage im wieder-vereinigten Deutschland

open access: yesLiterator, 1997
The mental-cultural situation of the re-united Germany In 1993 an exhibition presenting phenomena about the past, present and future of both East and West Germany took place in Berlin.
A. M. Rauch
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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