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Immunity to West Nile virus

Current Opinion in Immunology, 2004
Over the past five years, West Nile (WN) virus has emerged as an important public health concern in the United States. Recent studies from experimental models of WN virus infection have increased our understanding of its pathogenesis and immunity. These include the demonstration that the gene encoding 2'-5'oligoadenylate synthetase is responsible for ...
Tian, Wang, Erol, Fikrig
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West Nile Virus in the Americas

Medical Clinics of North America, 2008
Since the first detection of West Nile virus in the Western Hemisphere in 1999, the virus has spread rapidly across the North American continent and as far south as Argentina. An unprecedented pattern of large annual epidemics of human neuroinvasive disease continues in North America, resulting in considerable public health impact.
Lyle R, Petersen, Edward B, Hayes
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West nile virus encephalitis

Current Infectious Disease Reports, 2005
West Nile virus (WNV) is a small RNA virus. It was first isolated in the blood of a febrile woman in the West Nile district of Uganda in 1937. Although WNV has caused human disease in Africa and Europe since its identification, the first documented human infections occurred in the United States in 1999.
James L, Dean, Brandon J, Palermo
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West Nile Virus Encephalitis

New England Journal of Medicine, 2002
In August 1999, Dr. Deborah Asnis, an infectious-disease clinician in Queens, New York, reported two cases of encephalitis associated with muscle weakness to the New York City Department of Health....
Lyle R, Petersen   +2 more
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Persistence of West Nile virus

Microbes and Infection, 2015
West Nile virus (WNV) is a widespread global pathogen that results in significant morbidity and mortality. Data from animal models provide evidence of persistent renal and neurological infection from WNV; however, the possibility of persistent infection in humans and long-term neurological and renal outcomes related to viral persistence remain largely ...
Melissa N, Garcia   +2 more
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The Resurgence of West Nile Virus

Annals of Internal Medicine, 2012
Cases of West Nile virus in 2012 in the United States have exceeded those of any other year. This commentary discusses the endemic cases and asks whether they stem from a new strain of the virus, a...
Catherine M, Brown, Alfred, DeMaria
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West Nile virus infection

American Journal of Health-System Pharmacy, 2004
The epidemiology, virology, and transmission of West Nile virus (WNV) are reviewed, and the clinical features, diagnosis, and treatment of WNV infection are examined.WNV infection is caused by a flavivirus transmitted from birds to humans through the bite of culicine mosquitoes. WNV was discovered in the blood of a febrile woman from Uganda's West Nile
Roy, Guharoy   +3 more
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West Nile Virus Infection

American Journal of Roentgenology, 2005
Our objective is to present a brief review of the clinical aspects of West Nile virus infection with emphasis on the spectrum of MRI findings.West Nile virus infection has become endemic in the United States and radiologists should become aware of the diverse imaging appearances in the central nervous system.
Imad T, Zak   +4 more
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West Nile virus vaccines

Expert Opinion on Biological Therapy, 2004
West Nile virus (WNV) is a mosquito-borne flavivirus that is emerging as a global pathogen. In the last decade, virulent strains of the virus have been associated with significant outbreaks of human and animal disease in Europe, the Middle East and North America.
Hall, Roy A., Khromykh, Alexander A.
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West Nile virus in horses

Veterinary Record, 2006
Richard Drummond from defra replies: West Nile virus (wnv), as a cause of encephalomyelitis, has been a notifiable disease in horses since the introduction of the Infectious Diseases of Horses Order in 1987.
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