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Treatment of West syndrome

Brain and Development, 2011
West syndrome is one of the most refractory epileptic syndromes in infancy, and many researchers have made great effort to find optimal treatment modalities for this syndrome. In this review, previous literature on optimal treatments of West syndrome and its refractory nature were briefly presented, followed by an introduction of recent publication of ...
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Epidemiology of West syndrome in Singapore

Brain and Development, 2001
The incidence of West syndrome (WS) was determined by a search of reports of electroencephalograms (EEG) recorded in 1998 and 1999 in all public hospitals in Singapore. Amongst records of patients born in 1998, nine were found with EEG features of hypsarrhythmia or modified hypsarrhythmia with onset of seizures between January 1,1998 and December 31 ...
Hian-Tat Ong, Wei-Ling Lee
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Zonisamide in West syndrome

Brain and Development, 2001
Zonisamide (ZNS), a new antiepileptic drug developed in Japan, is being used as the initial treatment of West syndrome in some Japanese institutes. The reported response rate varied from 20 to 38%. The cryptogenic patients showed a better response than the symptomatic patients.
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PERIVENTRICULAR LEUKOMALACIA AND WEST SYNDROME

Developmental Medicine & Child Neurology, 1996
SUMMARYThe authors studied the clinical course and electroencephalograms (ÉEGs) of 27 patients with periventricular leukomalacia (PVL), to investigate the relation betwéen PVL and West syndrome. Seven of the 27 patients with PVL developed WS; in all seven the PVL was severe. Bilateral parieto‐occipital dominant irregular polyspike‐and‐wave (PO‐polySpW)
Akihisa Okumura   +3 more
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ORO-DENTAL MANIFESTATIONS IN WEST SYNDROME.

Current Topics in Medicinal Chemistry, 2019
BACKGROUND West Syndrome is a rare epileptic encephalopathy involving infantile spasms, altered electroencephalographic pattern with hypsarrhythmia, and psychomotor development delay.
F. della Vella   +8 more
semanticscholar   +1 more source

The West Syndrome: Developmental Aspects [PDF]

open access: possiblePediatrics International, 1987
AbstractThe electro‐clinical characteristics of childhood epilepsy are known to appear during the development of the brain and to change their features with age. Accordingly, developmental viewpoints are indispensable to researches on childhood epilepsy.Age‐dependent epileptic encephalopathy has the most remarkable developmental characteristics among ...
Yoko Ohtsuka   +2 more
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Magnetoencephalography in West syndrome

International Congress Series, 2002
Abstract Background: Localized lesions induce West syndrome (WS), and patients with West syndrome often subsequently develop focal seizures. Methods: We evaluated patients with West syndrome using magnetoencephalography (MEG). Fourteen patients who currently or previously had West syndrome were examined at 3 months to 6 years of age.
Osamu Matsuoka   +10 more
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What is West syndrome?

Brain and Development, 2001
The combination of axial spasms in clusters, hypsarrhythmia, and psychomotor delay beginning in the first year of life defines West syndrome. Variants of this classical triad comprise variations of age of onset ranging from the first month to 4 years, spasms that may be asymmetrical or combined with focal seizures, asymmetrical, synchronous or ...
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West syndrome with cerebellar porencephalus

Journal of Intellectual Disability Research, 1993
ABSTRACTThe authors report six very low birth weight newborn infants who had RDS, IVH and cerebellar porencephalus and later suffered from West syndrome. Four of them have been followed up to the present time and have had MRI scans performed. Their present clinico‐neurological features and MRI findings are described.
H. Koide, H. Shime
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West Syndrome Associated with Porencephaly

Pediatric Neurosurgery, 1994
A 3-year-old boy with West syndrome who was shown to have a cystic lesion on magnetic resonance imagings underwent surgical treatment. He had been initially managed with several antiepileptic drugs, but abnormalities on electroencephalography (EEG) persisted.
Manabu Kanayama   +6 more
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