Results 31 to 40 of about 3,893,039 (274)

The Effectiveness of Acth Therapy According to Etiology in Patients with West Syndrome and Its Long-Term Effects on Bone Mineral Metabolism and Adrenal Pathway

Çocuk Dergisi, 2022
Objective: West syndrome is the most common infantile epileptic encephalopathy, and ACTH or oral corticosteroids are frequently used in its treatment. The aim of this study was to evaluate the efficacy of ACTH therapy and its effects on bone metabolism ...
Mesut Güngör, Mine Düzgöl, Hülya Maraş Genç, Emek Uyur Yalçın, Filiz Mine Çizmecioğlu Jones, Bülent Kara   +5 more
doaj   +1 more source

The mystery of the Doctor's son, or the riddle of West syndrome. [PDF]

, 2002
Although the eponym "West syndrome" is used widely for infantile spasms, the originators of the term and the time frame of its initial use are not well known. This article provides historical details about Dr. West, about his son who had infantile spasms,
Baram, Tallie Z, Eling, Paul, Pomper, Joern, Renier, Willy O   +3 more
core   +2 more sources

Infantile Spasms: An Update on Pre-Clinical Models and EEG Mechanisms

Children, 2020
Infantile spasms (IS) is an epileptic encephalopathy with unique clinical and electrographic features, which affects children in the middle of the first year of life. The pathophysiology of IS remains incompletely understood, despite the heterogeneity of
Remi Janicot, Li-Rong Shao, Carl E. Stafstrom   +2 more
doaj   +1 more source

DMD and West syndrome

Neuromuscular Disorders, 2017
Duchenne Muscular Dystrophy (DMD) is the most frequent muscular dystrophy in childhood, with a worldwide incidence of one in 5000 live male births. It is due to mutations in the dystrophin gene leading to absence of full-length dystrophin protein. Central nervous system involvement is well-known in Duchenne Muscular Dystrophy.
Cardas, R, Iliescu, C, Butoianu, N, Seferian, A, Gataullina, S, Gargaun, E, Nectoux, J, Bienvenu, T, Craiu, D, Gidaro, T, Servais, L   +10 more
openaire   +4 more sources

Taking forward a 'One Health' approach for turning the tide against the Middle East respiratory syndrome coronavirus and other zoonotic pathogens with epidemic potential [PDF]

, 2016
The appearance of novel pathogens of humans with epidemic potential and high mortality rates have threatened global health security for centuries. Over the past few decades new zoonotic infectious diseases of humans caused by pathogens arising from ...
Abdulaziz N. Alagaili, Alagaili, Alimuddin Zumla, Arabi, Arabi, Azhar, Briese, Du, Esam I. Azhar, Eskild Petersen, Francine Ntoumi, Giuseppe Ippolito, Gossner, Haagmans, Hui, Hui, Ippolito, Jacobsen, Macete Eusebio, Markus Maeurer, Mathis, Matthew Bates, Matthew Cotten, Matthew Muturi, McCloskey, Memish, Mishal Khan, Mohd, Osman Dar, Peiris, Peter Mwaba, Petersen, Petersen, Pontiano Kaleebu, Rashid Ansumana, Reusken, Richard Kock, Sabir, Sayoki Mfinanga, Smith, The, Thiam, Uyeki, Wang, Zaki, Zumla, Zumla, Zumla   +47 more
core   +6 more sources

Burden of fetal alcohol syndrome in a rural West Coast area of South Africa [PDF]

, 2013
Background. Fetal alcohol syndrome (FAS) is common in parts of South Africa; rural residence is a frequently cited risk factor. We conducted a FAS school prevalence survey of an isolated rural community in a West Coast village of Western Cape Province ...
Chersich, Matthew, Olivier, L, Temmerman, Marleen, Urban, M, Viljoen, D   +4 more
core   +1 more source

Brain connectivity in West syndrome [PDF]

Seizure, 2014
Hypsarrhythmia, the pathognomonic EEG pattern of West syndrome, is typically characterized by a high amplitude, arrhythmic, and asynchronous pattern. While this severely aberrant pattern would suggest severe abnormalities in connectivity, coherence has not yet been systematically assessed in hypsarrhythmia.We evaluated the EEGs of 28 infants, 12 with ...
Scott A. Burroughs, Steven H. Mott, Richard P. Morse, Gregory L. Holmes, Gregory L. Holmes   +4 more
openaire   +3 more sources

Modernising epidemic science: enabling patient-centred research during epidemics [PDF]

, 2016
Background: Emerging and epidemic infectious disease outbreaks are a significant public health problem and global health security threat. As an outbreak begins, epidemiological investigations and traditional public health responses are generally mounted ...
Horby, Peter W., Rojek, Amanda M.
core   +3 more sources

Investigations in West Syndrome: Which, When and Why

Pediatric Neurology Briefs, 2015
Investigators from the National Infantile Spasms Consortium (NISC) in the USA studied the etiology of new-onset infantile spasms (IS) in 251 infants (mean age at onset, 7.1, range, 0.1-22.7 months).
Richard E Appleton
doaj   +1 more source

Clinical disorders affecting mesopic vision [PDF]

, 2006
Vision in the mesopic range is affected by a number of inherited and acquired clinical disorders. We review these conditions and summarize the historical background, describing the clinical characteristics alongside the genetic basis and molecular ...
Abramowicz M., Ahmed F., Ahmed F., Al-Kubaisy W., Asrat Y., Ayyagari R., Baillie I., Bergen H. R., Berson E., Bloem M., Bordley J., Bret-Dibat C., Brink E., Burstedt M., Burstedt M., Capon M., Carr R., Carr R., Chisholm C., Christian P., Cunier F., de Pee S., DOG, Donnen P., Duke-Elder S., Fishman G., Fuchs A., Fuchs A., Gross-Jendroska M., Guy J., Haidar J., Hartmann E., Hayashi T., Hayashi T., Heckenlively J., Kalloniatis M., Kamei M., Kellner U., Kolling G., Lauber H., Lei B., Lorenz B., Main A., Marmor M., Marmor M., McBain V., Mele L., Milam A., Miyake Y., Miyake Y., Miyake Y., Mizuo A., Morimura H., Nabakwe E., Nettleship E., Oguchi C., Onder C., Parker W., Perlman I., Pesudovs K., Phelan J., Polans A., Polkinghorne P., Ramalho R., Reiner J., Resnikoff S., Ripps H., Rosen D., Rosen D., Rougier M., Ruiz-Martin M., Saunders C., Sawyer R., Schaumberg D., Schemann J., Schlote T., Schubert G., Sharp D., Shaw C., Skinner H., Smith R. A. J., Sommer A., Somner A., Sorsby A., Souied E., Spalton D., Stephenson S., Stockman A., Tabata Y., Takeuchi T., Taren D., Thirkill C., Tielsch J., Underwood B., Uyemura M., Weinstein J., Weiss J., Weiss N., Wolf G., Wolf G., Wolfe J. E.   +100 more
core   +1 more source