Results 51 to 60 of about 9,392,646 (337)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

The Traumatic Mysticism of Othered Others: Blackness, Islam, and Esotericism in the Five Percenters

open access: yesCorrespondences, 2019
This article draws from black critical theory, Western esotericism studies, and scholarship in Islamic studies to articulate the Five Percenters as expressing what I call “traumatic mysticism.” I first articulate blackness as the esoteric secret of the ...
Biko Gray
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Myth in Black: Revisionismo ed epica in Django Unchained

open access: yesIperstoria, 2018
This article aims to investigate the role of the German mythology in Quentin Tarantino’s revisionist western Django Unchained (2012). According to the following analysis, the director uses the western formula and aesthetics to characterize Django as a ...
Marta Cafiso
doaj   +1 more source

Fa’atsiru Faqlidu Rokat Tase ‘ala ‘aqidatu as-shiyadin

open access: yesJournal of Comparative Study of Religions, 2021
Rokat Tase’ is a tradition or ancestral heritage that is still preserved by coastal communities, especially fishermen. In its implementation, several rituals have become their beliefs which have a major influence on the faith of the local community.
Farhah Farhah   +1 more
doaj   +1 more source

State Highlights v2/11/1953 [PDF]

open access: yes, 1953
This is the student newspaper from Western State High School, the high school that was on the campus of Western Michigan University, then called State Highlights, in ...
, Western State High School
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Il western come tremendismo. Cristo Versus Arizona di Camilo José Cela

open access: yesIperstoria, 2018
This essay aims to analyse one of Camilo José Cela’s last novels, Cristo versus Arizona (1988) by applying a thematic and formalist approach. It moves from the several terminological debates on the word “tremendismo” and from its pervasiveness within ...
Mauro Fradegradi
doaj   +1 more source

State Highlights 10/24/1941 [PDF]

open access: yes, 1941
This is the student newspaper from Western State High School, the high school that was on the campus of Western Michigan University, then called State Highlights, in ...
, Western State High School
core   +1 more source

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