Results 91 to 100 of about 25,475 (268)

Age-Stage, Two-Sex Life Table of Leptinotarsa decemlineata (Coleoptera: Chrysomelidae) Experiencing Cadmium Stress

open access: yesInsects
Cadmium in agricultural soils has emerged as a substantial threat to crop health and yields through its bioaccumulation along the food chain, with further repercussions for the growth, development, and population dynamics of herbivorous insects.
Bingyu He   +5 more
doaj   +1 more source

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

open access: yesAdvanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo   +17 more
wiley   +1 more source

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

open access: yesAdvanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang   +14 more
wiley   +1 more source

THE INFLUENCE OF THE MODERN CLIMATIC DYNAMICS ON THE SEMIDESERT LANDSCAPES OF TYULENY ISLAND IN THE NORTHWESTERN PART OF THE CASPIAN SEA

open access: yesЮг России: экология, развитие, 2014
The authors of the article reveal trends of climatic conditions’ changing and variability of hydro-thermal conditions in semi-desert landscapes of Island Tuleny in North-western part of the Caspian Sea, evaluate the different conditions’ contribution and
Z. V. Ataev   +2 more
doaj  

Long-Term Changes in Shelterbelt Stability Along the Taklimakan Desert Highway Revealed by Landsat Observations

open access: yesRemote Sensing
The Taklimakan Desert Highway shelterbelt is the world’s largest ecological protection system established along a highway in a shifting desert environment and plays a critical role in mitigating wind-blown sand hazards and ensuring transportation safety.
Shijie Wang   +4 more
doaj   +1 more source

Origin of mysterious geothermal gas emissions in the middle of the Western Desert, stable shelf area, Dakhla Oasis, Egypt. [PDF]

open access: yesSci Rep, 2023
Abdel Zaher M   +12 more
europepmc   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

open access: yesAdvanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu   +7 more
wiley   +1 more source

Late Miocene karst system at Sheikh Abdallah, between Bahariya and Farafra, Western Desert, Egypt: Implications for palaeoclimate and geomorphology

open access: yesGeologica Acta, 2009
The extensive spelean deposits in the Western Desert of Egypt at Crystal Mountain (Gebel Bellorat) are considered to be 11-10 Ma, confirming the ‘Vallesian’ estimate made by Heissig (1982).
H.A. WANAS   +4 more
doaj  

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