Results 121 to 130 of about 26,440 (305)

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Origins of the Western Desert language: convergence in linguistic and archaeological space and time models

, 2000
Recently linguists have adopted historical approaches to provide chronologies for the expansion of languages in Australia. McConvell (1996) has defined an approach he refers to as linguistic prehistory, in which the methods of comparative linguistics are
Veth, Peter
core  

THE INFLUENCE OF THE MODERN CLIMATIC DYNAMICS ON THE SEMIDESERT LANDSCAPES OF TYULENY ISLAND IN THE NORTHWESTERN PART OF THE CASPIAN SEA

Юг России: экология, развитие, 2014
The authors of the article reveal trends of climatic conditions’ changing and variability of hydro-thermal conditions in semi-desert landscapes of Island Tuleny in North-western part of the Caspian Sea, evaluate the different conditions’ contribution and
Z. V. Ataev, T. R. Balguev, V. V. Bratkov   +2 more
doaj  

Age-Stage, Two-Sex Life Table of Leptinotarsa decemlineata (Coleoptera: Chrysomelidae) Experiencing Cadmium Stress

Insects
Cadmium in agricultural soils has emerged as a substantial threat to crop health and yields through its bioaccumulation along the food chain, with further repercussions for the growth, development, and population dynamics of herbivorous insects.
Bingyu He, Jiebo Zhang, Yang Hu, Yi Zhang, Jianan Wang, Chao Li   +5 more
doaj   +1 more source

Origin of mysterious geothermal gas emissions in the middle of the Western Desert, stable shelf area, Dakhla Oasis, Egypt. [PDF]

Sci Rep, 2023
Abdel Zaher M, El-Hadidy M, El-Qady G, Rabeh T, Atya M, El-Hady S, Tantawy AA, El-Hemaly I, Al Deep M, Awad A, Salama H, Khalifa MM, Leila M.   +12 more
europepmc   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Late Miocene karst system at Sheikh Abdallah, between Bahariya and Farafra, Western Desert, Egypt: Implications for palaeoclimate and geomorphology

Geologica Acta, 2009
The extensive spelean deposits in the Western Desert of Egypt at Crystal Mountain (Gebel Bellorat) are considered to be 11-10 Ma, confirming the ‘Vallesian’ estimate made by Heissig (1982).
H.A. WANAS, M. PICKFORD, P. MEIN, H. SOLIMAN, L. SEGALEN   +4 more
doaj  

First definitive record of Abelisauridae (Theropoda: Ceratosauria) from the Cretaceous Bahariya Formation, Bahariya Oasis, Western Desert of Egypt. [PDF]

R Soc Open Sci, 2022
Salem BS, Lamanna MC, O'Connor PM, El-Qot GM, Shaker F, Thabet WA, El-Sayed S, Sallam HM.   +7 more
europepmc   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Antecedent moisture enhances early warning of atmospheric river flood hazards

Nature Communications
Atmospheric rivers are narrow bands of water vapor transport and serve as key drivers of water supplies and flood hazards in mid-latitude regions.
Mariana J. Webb, Christine M. Albano, Deniz Bozkurt, René D. Garreaud, Anna M. Wilson, Guo Yu, Michael L. Anderson, F. Martin Ralph   +7 more
doaj   +1 more source