Results 101 to 110 of about 1,843,358 (306)

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

RCAs within Western Europe [PDF]

This paper analyses the revealed comparative advantage for six European countries: Austria, France, Germany, Italy, the Netherlands and the UK. The results can be summarized as the follows: Italy always had a trade specialisation index which was well ...
Oelgemöller, Jens, Westermeier, Andreas
core  

Massive migration from the steppe is a source for Indo-European languages in Europe

, 2015
We generated genome-wide data from 69 Europeans who lived between 8,000-3,000 years ago by enriching ancient DNA libraries for a target set of almost four hundred thousand polymorphisms. Enrichment of these positions decreases the sequencing required for
A Keller, A Seguin-Orlando, Alan Cooper, Aleksandr Khokhlov, Alissa Mittnik, Anna Szécsényi-Nagy, AW Briggs, AW Briggs, Bastien Llamas, C Der Sarkissian, C Gamba, C Renfrew, Christina Roth, Christos Economou, D Reich, David Anthony, David Reich, DH Alexander, DH Alexander, DM Behar, Dorcas Brown, DW Anthony, Eadaoin Harney, Eszter Bánffy, Fredrik Hallgren, G Brandt, G Hellenthal, Guido Brandt, H Li, Harald Meller, I Lazaridis, I Olalde, Iosif Lazaridis, J Czebreszuk, Joachim Wahl, Johannes Krause, JP Mallory, Kristin Stewardson, Kurt Werner Alt, M Kircher, M Lipson, M Meyer, M Raghavan, Manuel A. Rojo Guerra, Matthias Meyer, Michael Francken, Michael Kunst, N Patterson, N Rohland, N Rohland, N Rohland, Nadin Rohland, Nick Patterson, Nicole Nicklisch, NM Myres, Oleg Mochalov, P Bellwood, P Ralph, P Skoglund, P Skoglund, P Skoglund, PA Underhill, Pavel Kuznetsov, Q Fu, Q Fu, Q Fu, Qiaomei Fu, Rafael Garrido Pena, RE Green, Roberto Risch, S Purcell, S Sawyer, Sandra L. Pichler, Susanne Friederich, Susanne Nordenfelt, Swapan Mallick, T Lassmann, TV Gamkrelidze, Valery Khartanovich, Vayacheslav Moiseyev, W Haak, Wolfgang Haak   +81 more
core   +2 more sources

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Interrelationships and Causal Linkages Between Socioeconomic and Environmental Factors [PDF]

The purpose of this study was to examine interrelationship and causal linkages between socioeconomic and environmental variables in OECD countries. To aid this study, a LISREL modelling tool was implemented. The findings of the study indicated that gross
Barre, Mike, DeCivita, Paul, Mariam, Yohannes, Urquhart, Lynda   +3 more
core   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Review of Festival Cities: Culture, Planning and Urban Life by John R. Gold and Margaret M. Gold

Journal of Festive Studies, 2023
Bernadette Quinn
doaj   +1 more source

Post-Korean monetary policies in Western Europe [PDF]

Monetary policy - Western Europe ; Economic conditions - Western ...
anonymous
core  

Mitochondria‐Specific Protein Delivery by Protease‐Triggered Release in Plants with Single‐Walled Carbon Nanotubes

Advanced Materials Technologies, EarlyView.
Polymer‐coated carbon nanotubes were engineered as protease‐responsive nanocarriers for protein delivery in intact plants. GFP cargo can be released by cytosolic phytaspase cleavage and subsequently targeted to mitochondria via an N‐terminal sequence, enabling controlled intracellular protein delivery without tissue damage and demonstrating stable ...
Simon Sau Yin Law, Takehiro Suzuki, Tsuyohiko Fujigaya, Keiji Numata   +3 more
wiley   +1 more source