Results 61 to 70 of about 1,060,633 (312)
Hints of Western Medicine from Chinese Medicine
Experimental Biology and Medicine, 2003 As a biochemist, I have been studying lipolytic and lipogenic pathways in fat cells since 1963. In 1966, I proposed a hormone-sensitive substrate theory in which catecholamines might not act on lipase but on substrate during their lipolytic processes.
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Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
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Transformative model of medical education [PDF]
Journal of Krishna Institute of Medical Sciences UniversityThe 'Western Medicine' came to India through th Portuguese in early 16 Century. However, it was not institutionalized in a concrete sense until British East India Company constructed hospital at Madras followed by Surat and Machhalipattam, which were ...
Vedprakash Mishra
doaj
INDIGENOUS MEDICINE AND MENTAL HEALTH [PDF]
Acta Colombiana de Psicología, 2006 The different medical alternatives used today by humanity enrich the prophylaxis as well as the diagnoses and the treatment of diseases when these are tackled within a multicausal framework. In this paper two of these alternatives are considered: Western
Vallejo Samudio, Álvaro Roberto
doaj
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
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EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Medisan, 2010 Con el objetivo analizar los principios sobre los cuales se sustenta la medicina oriental para verificar la presencia del asma, se revisaron documentos específicos sobre la materia, donde se incluía la valoración acerca de si las alteraciones energéticas
Ileana Cutiño Clavel +1 more
doaj
Introduction to Western Influences in Pre-Meiji Japanese Medicine [PDF]
, 1957 Gordon E. Mestler
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