Results 31 to 40 of about 42,152 (245)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Applied Sciences, 2023 Wettability is a key parameter for optimizing the residual oil recovery from geological rock formations and it provides a path for improved oil recovery and geo-storage of energy.
Abdul Majeed Shar +3 more
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Bioinspired Surfaces With Switchable Wettability
Frontiers in Chemistry, 2020 The surface wettability of plants exhibits many unique advantages, which enhances the environmental adaptability of plants. In view of the rapid development of responsive materials, smart surfaces have been explored extensively to regulate surface ...
Dong-Dong Han +6 more
doaj +1 more source
Recent Growth of Wettability Gradient Surfaces: A Review
Research, 2022 This review reports the recent progress and future prospects of wettability gradient surfaces (WGSs), particularly focusing on the governing principles, fabrication methods, classification, characterization, and applications.
Raza Gulfam, Yongping Chen
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Analyzing the wettability changes of rocks in various states of core plugs
Известия высших учебных заведений: Нефть и газCurrent core plugs preparation standards for laboratory studies are developed for water-wet reservoirs and do not consider other types of wettability. Researching how different core preparation methods affect laboratory studies and wettability changes is
M. S. Khorolskaya, H. O. Khorolsky
doaj +1 more source