Results 51 to 60 of about 43,700 (313)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Experimental study on the disintegration of granite residual soil under the combined influence of wetting–drying cycles and acid rain

Geomatics, Natural Hazards & Risk, 2019
Granite residual soil has obvious disintegration characteristics, resulting in serious water and soil losses in South China. There is a lack of studies on the disintegration of granite residual soil.
Weiping Liu, Xinqiang Song, Faming Huang, Lina Hu   +3 more
doaj   +1 more source

Experimental Study on Cracking Behaviour and Strength Properties of an Expansive Soil under Cyclic Wetting and Drying

Shock and Vibration, 2021
Expansive soil is characterized by its unique structural morphology and drastic volume change. With infrastructure increasingly constructed in expansive soil areas, engineering problems caused by the properties of expansive soils have attracted more ...
Tao Li, Yanqing He, Guokun Liu, Binru Li, Rui Hou   +4 more
doaj   +1 more source

Relationships between leaf and root area indices and soil suction induced during drying-wetting cycles [PDF]

, 2016
The stability and serviceability of geotechnical infrastructure may be affected by plant-induced soil suction during drying-wetting cycles, because an increase in suction would reduce hydraulic conductivity and also increase shear strength.
A. Garg, A.K. Leung, Angers, B.C.H. Hau, Brivio, Butler, C.W.W. Ng, Campbell, Carminati, Fan, Garg, Garg, Garg, Garg, Ghestem, Hau, Hupet, Impens, Kelliher, Ladd, Lam, Leung, Leung, López, Merrill, Mitsch, Murphy, Ng, Penman, Pollen-Bankhead, Qadir, Raich, Rasband, Reich, Ritchie, Ross, Salisbury, Simon, Smethurst, Smethurst, Sperry, Taha, TDOT, Veylon, Zhang, Zhang, Zhang   +46 more
core   +3 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Damage Features of Altered Rock Subjected to Drying-Wetting Cycles

Advances in Civil Engineering, 2018
An abandoned open pit was used as a tailing pond for a concentrating mill, with the height of the water surface subject to cyclic fluctuation. The effects of drying and wetting cycles on the mechanical parameters of pit rock were tested.
Zhe Qin, Xuxin Chen, Houli Fu
doaj   +1 more source

The Strength Behavior and Desiccation Crack Development of Silty Clay Subjected to Wetting–Drying Cycles

Frontiers in Earth Science, 2022
It is commonly accepted that wetting–drying cycles have an effect on the soil strength behavior. Crack development in soil is observed by many engineers during wetting–drying cycles, which may give a good explanation for the change in soil strength.
Yiliang Tu, Yiliang Tu, Rui Zhang, Zuliang Zhong, Hejun Chai   +4 more
doaj   +1 more source

Adjustment of Coatings Morphology and Particle Distribution of Layered Silicates by Freeze‐Drying for Improved Gas Barriers

Advanced Engineering Materials, EarlyView.
Freeze‐drying of layered silicate is the key to get coatings with superior gas barrier. Freeze‐drying of layered silicates modified with dodecylamine (DDA) is a highly effective technique for the preparation of barrier pigments that significantly mitigate the permeation of oxygen, water vapor, and hydrogen through polymer films containing these ...
Joshua Lommes, Moritz Bätcher, Andrea Deißenberger, Volkmar Stenzel, Andreas Hartwig   +4 more
wiley   +1 more source

Damage in porous media due to salt crystallization [PDF]

, 2010
We investigate the origins of salt damage in sandstones for the two most common salts: sodium chloride and sulfate. The results show that the observed difference in damage between the two salts is directly related to the kinetics of crystallization and ...
A. Nicolaescu, A. S. Goudies, B. Lubelli, Daniel Bonn, François Bertrand, Julie Desarnaud, N. Shahidzadeh-Bonn, Noushine Shahidzadeh-Bonn, S. Chatterji, Xavier Chateau   +9 more
core   +5 more sources