Results 111 to 120 of about 174,007 (375)

Characterization of linezolid-resistance-associated mutations in Mycobacterium tuberculosis through WGS.

Journal of Antimicrobial Chemotherapy, 2019
OBJECTIVES Linezolid is becoming an important antibiotic for treating MDR/XDR TB, but the mutations conferring resistance to linezolid remain inadequately characterized.
Rui Pi, Qingyun Liu, Q. Jiang, Q. Gao
semanticscholar   +1 more source

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

Advanced Science, EarlyView.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang, Shi‐Hao Bai, Shu‐Jin Song, Xiao‐Li Zhang, Xue‐Ying Shang, Zhao‐Ning Lu, Xiao‐Fang Cui, Xin‐Le Zhu, Ze‐Guang Han   +8 more
wiley   +1 more source

Antimicrobial Resistance and the Genomic Epidemiology of Multidrug-Resistant Salmonella enterica serovar Enteritidis ST11 in China

Frontiers in Bioscience-Landmark
Background: With the recent evolution of multidrug-resistant strains, the genetic characteristics of foodborne Salmonella enterica serovar Enteritidis and clinical isolates have changed. ST11 is now the most common genotype associated with S. Enteritidis
Jie Liu, Yue Hou, Linna Zhao, Gang Chen, Jialiang Chen, Qiang Zhao, Liyan Ye, Shenghui Cui, Chengbin Wang   +8 more
doaj   +1 more source

Mapping the Non‐Canonical Splicing Variants: Decrypting the Hidden Genetic Architecture of Idiopathic Male Infertility

Advanced Science, EarlyView.
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li, Yuge Chen, Dongdong Tang, Yuying Sheng, Xu Han, Hao Geng, Na Zhang, Zongliu Duan, Guanxiong Wang, Yang Gao, Rui Guo, Rong Hua, Zhiming Ding, Chuan Xu, Qunshan Shen, Zhen Yu, Bing Song, Mingrong Lv, Yuping Xu, Huan Wu, Ji Wu, Yunxia Cao, Xiaojin He   +22 more
wiley   +1 more source

Molecular characterization of Vibrio cholerae responsible for cholera epidemics in Uganda by PCR, MLVA and WGS

PLoS Neglected Tropical Diseases, 2018
Background For almost 50 years sub-Saharan Africa, including Uganda, has experienced several outbreaks due to Vibrio cholerae. Our aim was to determine the genetic relatedness and spread of strains responsible for cholera outbreaks in Uganda. Methodology/
G. Bwire, David A Sack, Mathieu Almeida, Shan Li, Joseph B Voeglein, A. Debes, A. Kagirita, A. Buyinza, C. G. Orach, O. C. Stine   +9 more
semanticscholar   +1 more source

SLPI⁺ AT2‐Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche

Advanced Science, EarlyView.
Integrating spatial transcriptomics and single‐cell RNA sequencing, this study identifies a novel subpopulation of SLPI⁺ AT2‐like cells at the invasive margin of lung adenocarcinoma (LUAD). These cells, through stromal crosstalk and Wnt pathway activation, promote tumor stemness and invasion.
Zhoufeng Wang, Guonian Zhu, Pan Tang, Yan Wang, Wenxin Luo, Wenpeng Song, Zhikang Pan, Bingjie Zheng, YongChao Jiang, Defu Xiao, Xin Jin, Yong Bai, Guowei Che, Weimin Li   +13 more
wiley   +1 more source

Extraction of carrier lifetime in Ge waveguides using pump probe spectroscopy [PDF]

, 2016
Carrier lifetimes in Ge-on-Si waveguides are deduced using time-resolved infrared transmission pump-probe spectroscopy. Dynamics of pump-induced excess carriers generated in waveguides with varying Ge thickness and width is probed using a CW laser.
Absil, P, Lepage, G, Pantouvaki, M, Srinivasan, Srinivasan Ashwyn, Van Campenhout, J, Van Thourhout, Dries, Verheyen, P   +6 more
core   +1 more source

Ethical and Psychosocial Issues in Whole Genome Sequencing (WGS) for Newborns

Pediatrics, 2019
WGS raises different ethical issues than previous uses of genomics in newborns. In this article, I review some of the ethical issues that have arisen in the past when genetic testing has been done in newborns.
J. Lantos
semanticscholar   +1 more source

Ruddlesden–Popper Structured Sr3Fe2O7−δ as Redox‐Activated CO2 Sorbents for Green Hydrogen Production

Advanced Energy and Sustainability Research, EarlyView.
A‐site and B‐site doped strontium ferrite‐type Ruddlesden–Popper oxides are evaluated as CO2 sorbents for glycerol‐based hydrogen production via sorption‐enhanced steam reforming. A Sr1.4Ca0.6Fe0.9Ni0.1O4−δ composition forms an active Sr3Fe2O7 phase, achieving ≈95 vol% H2 purity and over sixfold longer CO2 prebreakthrough time (tpb) than its perovskite
Mahe Rukh, Runxia Cai, Seyedamin Razavi, Sam Portillo, Yuge Yao, Luke Neal, Fanxing Li   +6 more
wiley   +1 more source

CARACTERIZACIÓN Y EVALUACIÓN DE CATALIZADORES DE NÍQUEL EN LA REACCIÓN WGS

Revista de Investigaciones Universidad del Quindío, 2013
La producción de hidrogeno es de vital importancia para diversos procesos industriales y en este contexto la reacción WGS es de gran utilidad para conseguir altos valores de pureza de este elemento, especialmente por su reciente uso en la obtención de ...
Maria do Carmo Rangel, Johana Rodriguez Ruiz, Edgardo Meza Fuentes   +2 more
doaj