Results 141 to 150 of about 13,569 (287)

Profiling of Integrin Isoforms on Lung‐Tropic Exosomes by Spectrally and Kinetically Multiplexed Single‐Molecule Imaging

open access: yesAdvanced Science, EarlyView.
A spectrally and kinetically multiplexed single‐molecule imaging method is developed, which achieved simultaneous imaging of 12 exosomal proteins at an unparalleled single‐copy resolution. It is found that co‐occurrence of α6 integrin and the pairing β counterpart on single exosomes is essential for lung targeting, providing valuable information for ...
Songlin Liu   +10 more
wiley   +1 more source

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

open access: yesAdvanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu   +10 more
wiley   +1 more source

日本語と中国語のin-situ wh疑問詞に関する対照研究 [PDF]

open access: yes
[[abstract]]本研究は、言語学の観点から日本語と中国語の疑問詞の統語的特徴と意味を対照し、移動しない疑問詞(in-situ wh-word) の性質を探求する。このような対照研究を通じて、言語の個別性及び普遍性を明らかにすることが目的である。[[sponsorship]]台灣日本語文學會[[conferencetype]]國內[[conferencedate]]20120317~20120317[[iscallforpapers]]Y[[conferencelocation]]臺北 ...
[[corresponding]]徐佩伶, 徐佩伶
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Dual‐Site Synergistic Mechanism via Single‐Atom and Vacancy Drives Lattice Oxygen Activation in Layered Double Hydroxides

open access: yesAdvanced Science, EarlyView.
A strategy utilizing high‐energy ion beam technology to engineer defects in layered double hydroxide (LDH) nanosheets enables the high loading of non‐noble metal Mo single atoms. The synergistic effect between oxygen vacancies and single atoms promotes a novel mechanism for lattice oxygen activation, thereby significantly enhancing the oxygen evolution
Shixin Wu   +9 more
wiley   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

open access: yesAdvanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu   +4 more
wiley   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

open access: yesAdvanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu   +14 more
wiley   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao   +11 more
wiley   +1 more source

Valence‐Engineering of CeO2 Redox Modulator Boosts the Oxygen Electrocatalysis Performance in Fe/Co Dual‐Atom Catalyst

open access: yesAdvanced Science, EarlyView.
Valence‐engineering of CeO2 redox modulator can remove the highly oxidative by‐products and accelerate the oxidation state transitions of Co/Fe centers in FeCo dual‐atom catalyst during oxygen reduction/evolution electrocatalysis. Therefore, the stability and activity issues are resolved, significantly enhancing the overall performance when used as an ...
Hengqi Liu   +10 more
wiley   +1 more source

Achieving Fast Charging and Superior Cycling Stability Single‐Crystal Ni‐Rich Cathodes by Ultrafast Aqueous Washing

open access: yesAdvanced Science, EarlyView.
Prolonged water washing severely damages the surface layered structure of single‐crystal Ni‐rich cathodes, forming a thick rock‐salt barrier. In contrast, our 3‐min ultrafast washing removes residual lithium while confining surface reconstruction to an ultrathin 2–4 nm layer, thereby unlocking excellent fast‐charging and cycling stability.
Kaixin Liu   +8 more
wiley   +1 more source

[[alternative]]The Acquisition of Wh-Word in Mandarin Chinese [PDF]

open access: yes
計畫編號:NSC87-2411-H032-005研究期間:199708~199807研究經費:161,000[[sponsorship ...
范瑞玲
core  

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