Results 121 to 130 of about 118,840,470 (284)

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

Advanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi, Qun Liu, Baohua Zou, Wenyuan Wang, Xinlong Qiao, Lin Gao, Chaoxu Miao, Ningning Huang, Shuqing Tang, Rui Guo, Changqing Zeng, Ce Jia, Yuanchao Xue, Xuejun Guo, Jianjun Chen, Huiwen Wang, Guangju Ji   +16 more
wiley   +1 more source

Le meilleur promoteur dans quel sens ? A closer look at French sluicing (with extra elements)

Nordlyd: Tromsø University Working Papers on Language & Linguistics
This paper addresses French sluicing, focusing on constructions in which a wh-remnant co-occurs with a non-wh-element, collectively referred to as Sweeping (Sluicing With Extra Elements Persist-ing, Temmerman 2019). Building on prior work, it introduces
Tanja Temmerman
doaj   +1 more source

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

Advanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang, Yu‐Xuan Bai, Geng G. Tian, Bin Zhang, Ding‐Yi Lu, Qing‐Ping Yao, Wen‐Hao Tian, Xiao‐Na Wei, Jing‐Ting Yang, Ze‐Yu Xiong, Yi Lu, Yu‐Tong Jiang, Chun‐Hui Cai, Yu‐Ming Lu, Xian‐Qing Jia, Li‐Li Jing, Bao‐Jun Yang, Ying‐Xin Qi, Xin‐Xin Han, Ji Wu, Wen‐Hui Lin   +20 more
wiley   +1 more source

In search of wh in-situ in Romance : an investigation in detective stories

, 2015
It is well known that languages differ with respect to the position of the wh-element in constituent questions. While in many languages these questions are generally formed by the fronting of the wh-element to a sentence-initial position, other languages
Quaglia, Stefano, Kaiser, Georg A.
core   +1 more source

Choose me! Optionality in wh-fronting and copy deletion: evidence for overt-covert movement in Valdôtain Patois

Glossa
In this paper, I discuss new data on wh-movement in the Francoprovençal language Valdôtain Patois (ValPa) in support of overt-covert movement: overt movement with deletion of higher copies.
Luisa Seguin
doaj   +2 more sources

Pressure‐Activated and Retained Blue Emission in Melamine Through Hydrogen‐Bond and Packing Regulation

Advanced Science, EarlyView.
Pressure treatment activates and retains bright blue emission in melamine (MA). The pressure‐modified hydrogen‐bonding network and molecular packing create a distinct local environment after decompression, changing the balance among competing excited‐state relaxation pathways and enabling retained emission.
Siyao Wang, Weiwei Dong, Shuo Yang, Jiayue Jiang, Yushuang Wang, Shuailing Ma, Peng Liu, Xiaodong Li, Haitao Wang   +8 more
wiley   +1 more source

Unlocking Li/Mg‐Based Photochemical Nitration Platforms for Anticancer Drug Discovery

Advanced Science, EarlyView.
Two low‐toxicity light main‐group metal photochemical systems based on lithium and magnesium are constructed for selective C(sp2)‐H (di)nitration of anilines. The obtained dinitrated products exhibit anti‐HCC (hepatocellular carcinoma) and anti‐KYSE30 cell activities, holding promise as novel antitumor candidates.
Qian Wan, Jiali Zhu, Shanshuo Liu, Luchuan Ou, Huizhen Wang, Yu Lan, Zhou Dong, Yihang Bai, Wei Yang, Shihan Liu, Yan Qiao, Shi‐Jun Li, Zhigang Ren, Linbin Niu   +13 more
wiley   +1 more source

Wh-island and D-linking

, 2016
The traditional observation that Chinese wh-arguments do not exhibit wh-island effects may be only apparent. Using evidence from ‘how-many’ constructions, it is shown that Chinese has wh-island effects even with wh-arguments.
楊中玉;許婷婷;菊島和紀
core   +1 more source

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

Advanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang, Tong Wan, Siyue Zhang, Yunzhen Jiang, Peng Su, Jixin Liu, Zhitong Chen, Jie Hao, Haoyu Wang, Bing Chen, Wenjing Zhao, Lijuan Wang, Tao Xing, Qihuang Zhang, Ulf Schmitz, Zhiyong Ding, Nicola Crosetto, Bingqiang Liu, Qifeng Yang   +18 more
wiley   +1 more source

Wh-ex-situ in Mandarin Chinese: Mapping Between Information Structure and Split CP

, 2014
International audienceThis paper examines the so-called wh-ex-situ phenomenon in Mandarin Chinese. It shows that there are four different types of wh-ex-situ in the left-periphery of Mandarin: Type I: extracted wh-topic, Type II: extracted wh-focus, Type
Pan, Victor Junnan
core