Results 31 to 40 of about 20,590 (288)

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan   +5 more
wiley   +1 more source

On wh-movement in Spanish Echo Questions

open access: yesBorealis: An International Journal of Hispanic Linguistics, 2017
This paper examines Spanish echo questions, an understudied phenomenon even in extensively described languages such as English. In particular, it focuses on a very particular type of echo questions, such as those made in response to a previous yes/no ...
Ekaterina Chernova
doaj   +1 more source

Wh-movement vs. scrambling: The brain makes a difference [PDF]

open access: yes, 2000
(no ...
Fiebach, Christian J.   +2 more
core  

D-Tree Grammars

open access: yes, 1995
DTG are designed to share some of the advantages of TAG while overcoming some of its limitations. DTG involve two composition operations called subsertion and sister-adjunction.
Rambow, Owen   +2 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Wh-questions in Japanese: scrambling, reconstruction, and wh-movement [PDF]

open access: yes, 2002
In this article, I discuss some important properties of wh-questions and wh-scrambling in Japanese. The questions I will address are (i) which instances of (wh-) scrambling involve reconstruction and (ii) how the undoing effects of scrambling can be ...
Sabel, Joachim
core  

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Speculations About Early Syntax: The Production of Wh-questions by Normally Developing French Children and French Children with SLI

open access: yesCatalan Journal of Linguistics, 2006
This paper examines the spontaneous (and elicited) production of questions in 3 typically developing French children (1;8-2;10) and 11 French children with SLI (3;10-9;1).
Cornelia Hamann
doaj   +1 more source

On the Application of Wh Movement and Inversion in Code-Switching Sentences [PDF]

open access: yes, 1984
Cet article étudie les contraintes sur l’application de mouvement Wh et d’inversion du sujet dans les phrases contenant un changement de code. L’auteur montre que ces contraintes découlent entièrement des principes de la grammaire tels qu’ils sont ...
Woolford, Ellen
core   +1 more source

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