Results 31 to 40 of about 254,103 (283)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Shape optimisation of rim structure of aluminium alloy car wheels based on 90° impact test
Scientific ReportsAutomotive wheels are critical components for vehicular safety, with the rim subjected primarily to radial bending loads during operation. Balancing rim thickness and structural integrity under these loading conditions is imperative.
Guangdong Zhang +8 more
doaj +1 more source
Nauka ta progres transportu, 2020 Purpose. The study is aimed at identifying the patterns of the load influence on the rail and the parameters of the two-layer lubrication on the development of the main rail defects, namely, lateral wear in the curved track sections. Methodology.
S. V. Voronin +4 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Numerical simulation on 90° impact test of aluminium alloy wheel with the effect of tyre
Scientific ReportsCar wheels are crucial to automobile safety, requiring a rigorous test before production. A 90° impact test simulates the frontal impact and its influences on the wheel structure, replicating dynamic driving conditions.
Guangdong Zhang +7 more
doaj +1 more source
Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout
Arthritis Care &Research, EarlyView.Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo +6 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler +20 more
wiley +1 more source
Механика машин, механизмов и материалов, 2011 In the paper considered the schematic circuit, operating principle and arrangement of components assemblies and mechanisms unified hydraulic control system and life support for the family prospective hydromechanical transmission MWTP.
Yu.I. Nikolaev +4 more
doaj
Advanced Engineering Materials, EarlyView.Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios +5 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.The community‐driven Platform MaterialDigital Core Ontology (PMDco) 3.0 is introduced as a Basic Formal Ontology‐aligned semantic backbone for the processing–structure–properties paradigm in Materials Science and Engineering. Modular engineering, automated releases, and validation workflows are highlighted and key semantic patterns for materials ...
Markus Schilling +15 more
wiley +1 more source