Results 41 to 50 of about 101,423 (307)

Interactive effects between CDHR3 genotype and rhinovirus species for diagnosis and severity of respiratory tract infections in hospitalized children

Microbiology Spectrum, 2023
Rhinovirus (RV) is the leading pathogen causing childhood wheezing, with rhinovirus C (RV-C) species reported to cause asthma exacerbation. Allele A of single-nucleotide polymorphism (SNP) CDHR3_rs6967330 upregulates epithelial expression of RV-C ...
Yu P. Song, Man F. Tang, Agnes S. Y. Leung, Kin P. Tao, Oi M. Chan, Gary W. K. Wong, Paul K. S. Chan, Renee W. Y. Chan, Ting F. Leung   +8 more
doaj   +1 more source

Prevalence and risk factors associated with wheezing in the first year of life

Jornal de Pediatria, 2014
OBJECTIVE: to investigate the prevalence and risk factors associated with wheezing in infants in the first year of life. METHODS: this was a cross-sectional study, in which a validated questionnaire (Estudio Internacional de Sibilancias en Lactantes
Olivia A. A. Costa Bessa, Álvaro J. Madeiro Leite, Dirceu Solé, Javier Mallol   +3 more
doaj   +1 more source

Prevalence and Determinants of Wheezing and Bronchodilatation in Children With Cystic Fibrosis: A Retrospective Cohort Study

Frontiers in Pediatrics, 2022
BackgroundMany patients with cystic fibrosis (CF) wheeze, and are dubbed as having CF-asthma. Understanding the determinants of such wheezing may avoid unnecessary treatments and open newer treatment avenues.ObjectivesMain: To evaluate the prevalence and
Francois Galodé, O. Ladipo, A. Andrieux, H. Feghali, S. Bui, Michael Fayon, Michael Fayon   +6 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Vitamin D Level and Immune Modulation in Children with Recurrent Wheezing

Children
Introduction and aim: A direct causal relationship between vitamin D (vit D) deficiency and recurrent wheezing has not been proven. The present study investigated the role of vit D in enhancing the risk of asthma or recurrent wheezing by modifying the ...
Gavriela Feketea, Emilia Vassilopoulou, Oana Andreescu, Elena Camelia Berghea, Raluca Maria Pop, Octavia Sabin, Mihnea Zdrenghea, Ioana Corina Bocsan   +7 more
doaj   +1 more source

Recruiting ethnic minority participants to a clinical trial: a qualitative study [PDF]

, 2013
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non ...
Griffiths, C, Grigg, J, Macneill, V, Nwokoro, C, Seale, C   +4 more
core   +2 more sources

Effect of Foot Orthoses on Midfoot Pain and the Volume of Bone Marrow Lesions in the Midfoot: A Randomized Mechanism of Action Study

Arthritis Care &Research, EarlyView.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

Maternal exposure to smoking and wheezing phenotypes in children: a cohort study of the Japan Environment and Children’s Study

BMC Pediatrics
Background Previous studies have shown that prenatal maternal smoking and maternal secondhand smoke exposure during pregnancy were associated with an increased risk of wheezing and asthma development.
Takuya Wada, Yuichi Adachi, Shokei Murakami, Yasunori Ito, Toshiko Itazawa, Akiko Tsuchida, Kenta Matsumura, Kei Hamazaki, Hidekuni Inadera, on behalf of the Japan Environment and Children’s Study Group   +9 more
doaj   +1 more source

Temporal Trends and Short‐ and Long‐Term Mortality of People With Acute Myocardial Infarction and Rheumatoid Arthritis: A Nationwide Cohort Study

Arthritis Care &Research, EarlyView.
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A. Mamas   +8 more
wiley   +1 more source

Human Metapneumovirus Infection is Associated with Severe Respiratory Disease in Preschool Children with History of Prematurity

Pediatrics and Neonatology, 2016
Human metapneumovirus (HMPV) is a recently discovered respiratory pathogen of the family Paramyxoviridae, the same family as that of respiratory syncytial virus (RSV).
Krishna Pancham, Iman Sami, Geovanny F. Perez, Shehlanoor Huseni, Bassem Kurdi, Mary C. Rose, Carlos E. Rodriguez-Martinez, Gustavo Nino   +7 more
doaj   +1 more source