Results 51 to 60 of about 27,884 (312)

Effects of Cavitation on Rotordynamic Force Matrices [PDF]

open access: yes, 1988
When designing a turbomachine, particularly one which is to operate at high speed, it is important to be able to predict the fluid-induced forces, both steady and unsteady, acting on the various components of the machine.
Arndt, N., Brennen, C. E., Franz, R.
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

The Influence of Swirl Brakes on the Rotordynamic Forces Generated by Discharge-to-Suction Leakage Flows in Centrifugal Pumps [PDF]

open access: yes, 1993
Increasing interest has been give to swirl brakes as a means of reducing destabilizing rotordynamic forces due to leakage flows in new high speed rocket turbopumps.
Acosta, Allan J.   +3 more
core  

Fluid Flow Equations for Rotordynamic Flows in Seals and Leakage Paths [PDF]

open access: yes, 2001
Fluid-induced rotordynamic forces produced by the fluid in an annular seal or in the leakage passage surrounding the shroud of a pump or turbine, are known to contribute substantially to the potential excitation forces acting on the rotor.
Brennen, C. E., Hsu, Y.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Rotordynamic Forces on Centrifugal Pump Impellers [PDF]

open access: yes, 1987
The asymmetric flow around an impeller in a volute exerts a force upon the impeller. To study the rotordynamic force on an impeller which is vibrating around its machine axis of rotation, the impeller, mounted on a dynamometer, is made to whirl in a ...
Acosta, A. J.   +4 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Impeller-Induced Rotor-Dynamic Forces [PDF]

open access: yes, 1989
The flow through and around the rotor of a turbomachine exerts a force on the rotor and, hence, rotor shaft and bearing system. In some circumstances this force may lead to excitation of shaft whirl in the direction of impeller rotation.
Acosta, Allan J.   +2 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Laser Velocimeter Measurements in the Leakage Annulus of a Whirling Shrouded Centrifugal Pump [PDF]

open access: yes, 1994
Previous experiments conducted in the Rotor Force Test Facility at the California Institute of Technology have thoroughly examined the effect of leakage flows on the rotordynamic forces on a centrifugal pump impeller undergoing a prescribed circular ...
Acosta, A. J.   +5 more
core  

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