Results 71 to 80 of about 90,310 (310)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Infrabarrels Are Layer 6 Circuit Modules in the Barrel Cortex that Link Long-Range Inputs and Outputs

Cell Reports, 2017
The rodent somatosensory cortex includes well-defined examples of cortical columns—the barrel columns—that extend throughout the cortical depth and are defined by discrete clusters of neurons in layer 4 (L4) called barrels.
Shane R. Crandall, Saundra L. Patrick, Scott J. Cruikshank, Barry W. Connors   +3 more
doaj   +1 more source

Differential biomechanics determine rat whisker airflow responses.

, 2023
(A) Head of a deeply anesthetized rat. Note the thin whisker diameter of the lSO whisker. (B) Micrograph of the initial segments of lSO and E1 whiskers (top). Photograph of lSO and E1 whiskers (bottom). Scale: 1 mm. Scale: 100 μm.
Ben Gerhardt (16503141), Miguel Concha-Miranda (6683318), Varun Sharma (4971478), Ana Rita Mendes (16503138), Matias Mugnaini (7795139), Dhruv Mehrotra (16503132), Michael Brecht (698823), Federico Davoine (16503135), Ann M. Clemens (16503144)   +8 more
core   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

The Room-Temperature Chemiresistive Properties of Potassium Titanate Whiskers versus Organic Vapors

Nanomaterials, 2017
The development of portable gas-sensing units implies a special care of their power efficiency, which is often approached by operation at room temperature.
Alexey S. Varezhnikov, Fedor S. Fedorov, Igor N. Burmistrov, Ilya A. Plugin, Martin Sommer, Andrey V. Lashkov, Alexander V. Gorokhovsky, Albert G. Nasibulin, Denis V. Kuznetsov, Michail V. Gorshenkov, Victor V. Sysoev   +10 more
doaj   +1 more source

Texture Signals in Whisker Vibrations

Journal of Neurophysiology, 2006
Rodents excel in making texture judgments by sweeping their whiskers across a surface. Here we aimed to identify the signals present in whisker vibrations that give rise to such fine sensory discriminations. First, we used sensors to capture vibration signals in metal whiskers during active whisking of an artificial system and in natural whiskers ...
Hipp, J., Arabzadeh, E., Zorzin, E., Conradt, J., Kayser, C., Diamond, M. E., König, P.   +6 more
openaire   +5 more sources

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Specific and Non-Specific Thalamocortical Afferents to the Whisker–Related Sensory Cortical Region in Rats with Congenital Hypothyroidism [PDF]

Journal of Kerman University of Medical Sciences, 2015
Background & Aims: Thyroid hormones are of great importance in the development of the central nervous system. Congenital hypothyroidism may affect the reorganization of specific and non-specific thalamocortical afferents to whisker–related sensory (wS1 ...
Mohammad-Reza Afarinesh, Gila Behzadi
doaj  

Shape effect of whisker on Al2O3/SiC whisker composites.

Journal of the Japan Society of Powder and Powder Metallurgy, 1990
The mechnical properties of 20vol%-SiC whisker reinforced A1203-matrix composites were investigated. Composites are produced using two types of whiskers with 0.5μm and 0.8μm in diameter respectively. Also, α and γ alumina were used as starting materials for matrix. The composites were prepared by hot pressing mixtures of alumina powder containing 20vol%
Watanabe, Hidemi, Nakahira, Atushi, Niihara, Koichi   +2 more
openaire   +2 more sources

Effect of sensory deprivation and Locus Coeruleus (LC) electrical stimulation on the response properties of layer IV barrel cortex neurons in male rats [PDF]

Introduction: Barrel cortex of rodents is responsible for sensory information processing from muzzle whiskers. Locus coeruleus (LC) as the main source of norepinephrine (NE) in the cortex, is effective on the sensory information processing. Methods:
شمسی زاده, علی, سیاه پشت خاچکی, علی, شیبانی, وحید, شیخکانلوی میلان, حمید, آفرینش, محمدرضا   +4 more
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