Results 51 to 60 of about 3,998,673 (252)
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
ПРИМЕНЕНИЕ ЗАПУТЫВАЮЩИХ ПРЕОБРАЗОВАНИЙ В КРИПТОГРАФИИ
Безопасность информационных технологий, 2009 The author considers various aspects of obfuscation technique towards white-box cryptography and its application for DRM solutions. This paper covers questions related with transforming symmetric encryption schemes into asymmetric and designing ...
Евгений Юрьевич Родионов
doaj
On the (Im)possibility of Preventing Differential Computation Analysis with Internal Encodings
Transactions on Cryptographic Hardware and Embedded SystemsWhite-box cryptography aims at protecting implementations of cryptographic algorithms against a very powerful attacker who controls the execution environment. The first defensive brick traditionally embedded in such implementations consists of encodings,
Laurent Castelnovi, Agathe Houzelot
doaj +1 more source
GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors
FEBS Open Bio, EarlyView.GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille +6 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub +24 more
wiley +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
On the practical security of white-box cryptography [PDF]
, 2020 Cryptography studies how to secure communications and information. The security of a cryptosystem depends on the secrecy of the underlying key. White-box cryptography explores methods to hide a cryptographic key into some software deployed in the real ...
WANG, Junwei
core +1 more source
Transactions on Cryptographic Hardware and Embedded SystemsWhite-box cryptography (WBC) seeks to protect secret keys even if the attacker has full control over the execution environment. One of the techniques to hide the key is space hardness approach, which conceals the key into a large lookup table generated ...
Xiangren Chen +8 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source