Results 41 to 50 of about 11,832,712 (294)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Resistant Hypertension: Detection, Evaluation, and Management
RUHS Journal of Health Sciences, 2023 Treatment resistant hypertension (RH) is an important clinical problem. Its prevalence in clinical practice ranges from 10-20%. It has been defined as failure to achieve target blood pressure (BP), usually >140/90 mmHg after taking 3 or more anti ...
Abhishek Sanadhya
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Frontiers in Plant Science, 2023 IntroductionSesame seeds have become an irreplaceable source of edible oils and food products with rich nutrients and a unique flavor, and their metabolite contents and physiological functions vary widely across different seed coat colors.
Han Wang +13 more
doaj +1 more source
Pseudoresistant Hypertension Attributed to White-Coat Effect [PDF]
Hypertension, 2012 See related article, pp 564–571 An increase in blood pressure (BP) when taken in the office setting was recognized as early as 1940, when Ayman and Goldshine1 reported that BP readings measured in the clinic were higher than BP recorded in the home.
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
EFFECT OF TRANSFERRIN POLYMOROPHISM ON REPRODUCTIVE TRAITS OF BLACK BENGAL GOAT [PDF]
Exploratory Animal and Medical Research, 2018 The present investigation was carried out to find out the relationship of biochemically polymorphic blood protein transferrin with important reproductive traits in adult Black Bengal goats.
Rajesh Paul +3 more
doaj
P3.04 AORTIC STIFFNESS IS INDEPENDENTLY ASSOCIATED WITH WHITE COAT EFFECT
Artery Research, 2009 Introduction: The difference between systolic blood pressure (SBP) measured in clinic and during the daytime phase of ambulatory BP measurement (ABPM) (Δclinic-day ABPM SBP) has been used as a measure of white-coat effect.
C.A. Taylor +3 more
doaj +1 more source