Results 41 to 50 of about 61,194 (254)

Resistant Hypertension: Detection, Evaluation, and Management

open access: yesRUHS Journal of Health Sciences, 2023
Treatment resistant hypertension (RH) is an important clinical problem. Its prevalence in clinical practice ranges from 10-20%. It has been defined as failure to achieve target blood pressure (BP), usually >140/90 mmHg after taking 3 or more anti ...
Abhishek Sanadhya
doaj   +1 more source

Pseudoresistant Hypertension Attributed to White-Coat Effect [PDF]

open access: yesHypertension, 2012
See related article, pp 564–571 An increase in blood pressure (BP) when taken in the office setting was recognized as early as 1940, when Ayman and Goldshine1 reported that BP readings measured in the clinic were higher than BP recorded in the home.
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Genetic mapping of QTLs controlling brown seed coat traits by genome resequencing in sesame (Sesamum indicum L.)

open access: yesFrontiers in Plant Science, 2023
IntroductionSesame seeds have become an irreplaceable source of edible oils and food products with rich nutrients and a unique flavor, and their metabolite contents and physiological functions vary widely across different seed coat colors.
Han Wang   +13 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

EFFECT OF TRANSFERRIN POLYMOROPHISM ON REPRODUCTIVE TRAITS OF BLACK BENGAL GOAT [PDF]

open access: yesExploratory Animal and Medical Research, 2018
The present investigation was carried out to find out the relationship of biochemically polymorphic blood protein transferrin with important reproductive traits in adult Black Bengal goats.
Rajesh Paul   +3 more
doaj  

P3.04 AORTIC STIFFNESS IS INDEPENDENTLY ASSOCIATED WITH WHITE COAT EFFECT

open access: yesArtery Research, 2009
Introduction: The difference between systolic blood pressure (SBP) measured in clinic and during the daytime phase of ambulatory BP measurement (ABPM) (Δclinic-day ABPM SBP) has been used as a measure of white-coat effect.
C.A. Taylor   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Reduction of white coat effect by cilnidipine in essential hypertension [PDF]

open access: yesAmerican Journal of Hypertension, 2001
Stress elevates blood pressure (BP) by increased sympathetic nerve activity. Cilnidipine, a novel dihydropyridine calcium antagonist that has inhibitory actions on N-type as well as L-type voltage-dependent calcium channels, has been reported to attenuate the cold stress-induced increase in plasma norepinephrine and BP in rats.
S, Morimoto   +9 more
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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