Results 221 to 230 of about 23,238 (253)

Accuracy of surrogate outcomes in predicting true endpoints of surgical periodontal therapy. A narrative review with a 20‐year longitudinal analysis

Periodontology 2000, EarlyView.
Abstract Background Periodontal clinical trials commonly use surrogate end points (e.g., probing pocket depth [PPD], clinical attachment level [CAL], bleeding on probing [BoP], and composite scores such as the Periodontal Risk Score [PRS]) for efficiency, yet tooth loss, treatment burden/cost, and re‐treatment are the definitive patient‐relevant ...
Muhammad H. A. Saleh, Abdusalam E. Alrmali, Fatemeh SamavatiJame, Hamzeh Almanshi, Shahad Alhazmi, Sawsan Abu‐Reyal, Hom‐Lay Wang, Ann Decker   +7 more
wiley   +1 more source

The Impact of White-Coat Hypertension on Cardiac Mechanics. [PDF]

J Clin Hypertens (Greenwich), 2016
Tadic M, Cuspidi C, Ivanovic B, Vukomanovic V, Djelic M, Celic V, Kocijancic V.   +6 more
europepmc   +1 more source

The Association of Pretransplant CD4 Count With Post‐Kidney Transplant Infectious Outcomes Among Persons With HIV

Transplant Infectious Disease, EarlyView.
In this multi‐center study comparing persons with HIV with pre‐kidney transplant CD4 < 350 cells/µL to those with ≥ 350 cells/µL, we found no difference in relative risk of infection in the first year‐post kidney transplant, 5‐year graft survival, and 5‐year overall survival.
Rebecca H. Burns, Sara Booth, Christin Rogers Marks, Christine M. Durand, Jonathan Hand, Maheen Z. Abidi, Maricar Malinis, Brittany Barnaba, Martha Pavlakis, Douglas Krakower, Carolyn D. Alonso, Audrey Le‐Mahajan   +11 more
wiley   +1 more source

Core decompression augmented with bone marrow aspirate concentrate for refractory distal sesamoid bone pathology in horses: A retrospective clinical study

Veterinary Surgery, EarlyView.
Abstract Objective To determine short‐ and long‐term outcomes of core decompression combined with autologous bone marrow aspirate concentrate (BMAC) in treating moderate‐to‐severe refractory distal sesamoid bone (DSB) trabecular pathology in horses. Study design Retrospective observational study. Animals A total of 21 client‐owned Warmblood horses with
Grigorios Maleas, Mahmoud Mageed, Kristyna Hargitaiova   +2 more
wiley   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study

Experimental Physiology, EarlyView.
Abstract Internal carotid artery (ICA) dissection is a rare and potentially devastating cause of cerebral ischaemia, initiated by an intimal tear or rupture of the vasa vasorum, that can lead to an intraluminal thrombus, vascular stenosis, occlusion, or dissecting aneurysm formation.
Damian M. Bailey, Richard G. Davies, Brenig L. Gwilym, Benjamin S. Stacey, Danny Walmsley, Michael H. Lewis, Josip Butkovic, Ivan Mumlek, Brad Perry, Zvonomir Vrselja, Shigehiko Ogoh, James A. Pawelczyk, Mohamad Bashir, Richard D. White, Ian M. Williams   +14 more
wiley   +1 more source

Whole‐body hot water immersion effect on cerebral haemodynamics and subsequent cerebrovascular reactivity to carbon dioxide

Experimental Physiology, EarlyView.
Abstract To test the hypothesis that hot water immersion (HWI) improves cerebrovascular function via shear‐mediated mechanisms, this study determined cerebrovascular reactivity to carbon dioxide (CVRCO2${\mathrm{CV}}{{\mathrm{R}}_{{\mathrm{C}}{{\mathrm{O}}_2}}}$) before and after 60 min of 39°C HWI and a 21°C air control (CON) in 15 healthy ...
Samuel F. Leaney, Ester Tommasini, Guto W. Hughes, Alison M. Shepherd, Nyah D. Kingdon, Justin S. Lawley, Geoff B. Coombs, Jonathan P. Moore, Samuel J. Oliver   +8 more
wiley   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Effect of repeated hot water immersion on cognitive performance, cerebrovascular function, sleep and biomarkers of neurodegeneration in older adults

Experimental Physiology, EarlyView.
Abstract Ageing is associated with cognitive decline and increased risk of developing neurodegenerative disease. Repeated passive heating, using hot water immersion (HWI), may improve cognitive performance via improved cerebral oxygenation, but this is yet to be examined in older adults.
Daniel D. Piccolo, Jo Corbett, Joseph T. Costello, Thomas B. Williams, Thomas J. James, Janis K. Shute, Mohammad G. A. Alnajjar, Luke C. Hudson, Poppy A. Marsh, Veronika Praskacova, Harry S. Mayes, Michael Tipton, Maria Perissiou, Melitta A. McNarry, Kelly A. Mackintosh, Zoe L. Saynor, Anthony I. Shepherd   +16 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source