Results 41 to 50 of about 4,710,457 (313)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
“The devil looks ten times worse with a white face”: Colours in Richard Brome’s The English Moor
E-REA, 2015 This paper purposes to investigate the multiple meanings of the black and white opposition which lies at the basis of the plot of Richard Brome’s The English Moor.
Cristina PARAVANO
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Sensory patterns and oxygen consumption kinetics in the oxidation of white, rosé and sparkling wines
OENO OneThe present work studies the sensory changes caused by the consumption of oxygen of two whites, one rosé and one sparkling wine. Wines were subjected to different doses of O2 (0, 6, 12 and 35 mg/L over the stoichiometric to consume total SO2) and ...
A. Manuel Aragón-Capone +3 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Le symbolisme des couleurs liturgiques dans le rite Romain médiéval / The Symbolism of Liturgical Colours in the Medieval Roman Rite [PDF]
Anastasis: Research in Medieval Culture and Art, 2015 After long periods of not having an established Liturgy dressing code in the Latin Church, the Cardinal Lotario di Segni, who became Pope Innocent III, wrote a treatise, De sacro altaris mysterio, Monumenta studia instrumenta liturgica, in 1195, having ...
Daniel Iacobuţ
doaj
Emergence of White Organic Light-Emitting Diodes Based on Thermally Activated Delayed Fluorescence
Applied Sciences, 2018 Recently, thermally activated delayed fluorescence (TADF) organic light-emitting diodes (OLEDs) have attracted both academic and industrial interest due to their extraordinary characteristics, such as high efficiency, low driving voltage, bright ...
Peng Xiao +5 more
doaj +1 more source