Results 71 to 80 of about 10,512,321 (293)

How Autonomy Can Legitimate Beneficial Coercion [PDF]

open access: yes, 2017
Respect for autonomy and beneficence are frequently regarded as the two essential principles of medical ethics, and the potential for these two principles to come into conflict is often emphasised as a fundamental problem.
White, Lucie
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Recent Developments in Tandem White Organic Light-Emitting Diodes

open access: yesMolecules, 2019
Tandem white organic light-emitting diodes (WOLEDs) are promising for the lighting and displays field since their current efficiency, external quantum efficiency and lifetime can be strikingly enhanced compared with single-unit devices.
Peng Xiao   +3 more
doaj   +1 more source

Teaching Queer Cinema With Independent Media [PDF]

open access: yes, 2012
In lieu of an abstract, this is the article\u27s introductory paragraph: One of the most exciting dimensions of teaching film (and popular culture) is learning what students already know and then generating an informed and critical epistemology from the ...
White, Patricia
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

ELEC6021 Research Methods: Report Writing [PDF]

open access: yes, 2013
Slides and Handouts for this part of the ...
White, Su
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

REWRITING THE WOMEN OF BREWSTER PLACE: MALE VOICES / RÉÉCRITURE DU SÉRIAL THE WOMEN OF BREWSTER PLACE: LES VOIX MASCULINS / RESCRIEREA SERIALULUI FEMEILE DIN BREWSTER: VOCILE MASCULINE [PDF]

open access: yesStudii si Cercetari Filologice: Seria Limbi Straine Aplicate, 2013
Gloria Naylor’s The Men of Brewster Place (1994) relates the saga of black men in the urban environment of the same name. Coming from different horizons, each with a different and individual story, these men arrive at Brewster Place hoping to cope with
Kouadio Germain N’Guessan
doaj  

City rivalries and the modernisation of Eighteenth-Century London, 1720-1770 [PDF]

open access: yes, 2010
Longstanding rivalries between the cities of London and Westminster came to a head in the 1730s with the decision by Parliament to build a new bridge at Westminster. Opened in 1750 the bridge seemed to threaten the commercial existence of the City.
White, Jerry
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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