Results 71 to 80 of about 4,710,457 (313)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Portrait of Glenn Murcutt, c 1980s [picture] /
, 1980 Title from inscription on reverse.; Condition: Good.; Inscription: "Portrait of Glen [i.e. Glenn] Murcutt, c 80s.
White, Jill.
core
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
David Moore at work photographing at Windsor, N.S.W. for Gillette advertisement, 1959 [picture] /
, 1959 Title from inscription on reverse.; Condition: Good.; Inscription: "David Moore at work photographing at Windsor, N.S.W. for "Gillette" advertisement, 1959.
White, Jill.
core
First page of a newsprint handbill detailing membership information for White Man's Union Association of Grimes County, Texas including the Constitution, By-Laws, and Rules of ...
White Man's Union Association
core +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 1927 A letter from Marcus White to his wife in Worcester, Massachusetts, describing the train ride to New York City and his fun-filled activities while ...
White, Marcus W.
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
David Moore being photographed by Max Dupain in Clarence Street Studio, 1959 [picture] /
, 1959 Title from inscription on reverse.; Condition: Good.; Inscription: "David Moore being photographed by Max Dupain in Clarence Street Studio, 1959.
White, Jill.
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source