Results 91 to 100 of about 3,006,200 (291)

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

Analyzing the Network Response Time and Load Balancing [PDF]

open access: yes
This paper describes the network response time which represent a significant indicator for network performance and how load balancing can improve the network performance.response time, load balancing, throughput, network ...
Madalina MLAK
core  

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Feedback Structures Generating Policy Exposure, Gatekeeping, and Care Disruption in Transgender and Gender Expansive Healthcare

open access: yesSystems
Transgender and gender-expansive (TGE) communities face persistent health inequities that are reproduced through everyday administrative and clinical encounters across care systems.
Braveheart Gillani   +7 more
doaj   +1 more source

David Moore being photographed by Max Dupain in Clarence Street Studio, 1959 [picture] /

open access: yes, 1959
Title from inscription on reverse.; Condition: Good.; Inscription: "David Moore being photographed by Max Dupain in Clarence Street Studio, 1959.
White, Jill.
core  

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen   +6 more
wiley   +1 more source

Letter from Marcus White, New York City, New York, to Wife and Family, Worcester, Massachusetts, May 24, 1927

open access: yes, 1927
A letter from Marcus White to his wife in Worcester, Massachusetts, describing the train ride to New York City and his fun-filled activities while ...
White, Marcus W.
core  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

Comparative Metabolomics Reveals the Adaptive Strategy of White Auricularia cornea to Bamboo Substrate Variation

open access: yesJournal of Fungi
To address the “fungus-forest conflict” in the edible mushroom industry and the challenge of resource utilization for bamboo substrate waste, this study focused on white Auricularia cornea, and cultivation systems were established with bamboo substrate ...
Xianqi Shan   +11 more
doaj   +1 more source

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