Results 121 to 130 of about 957,445 (344)

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji   +13 more
wiley   +1 more source

Elevated white blood cell counts and risk of metabolic syndrome: a dose-response meta-analysis

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2019
Background and Aim: Elevated white blood cell count has been a known risk factor for cardiovascular diseases. Cardiometabolic diseases have some risk factors in common.
Roholla Hemmati   +4 more
doaj  

Immunomodulation by ectosomes [PDF]

open access: yes, 2010
Considerable progress has been made in recognizing microvesicles as important mediators of intercellular communication rather than irrelevant cell debris.
Eken, Ceylan
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

Neuroimaging Biomarkers in Paediatric Sickle Cell Disease

open access: yes, 2015
Sickle Cell Disease (SCD) is a collection of genetic haemoglobinopathies, the most common and severe being homozygous sickle cell anaemia. In the UK, it has been estimated that 1 in 2000 children are born with SCD. The disease is characterised by chronic
Kawadler, JM
core  

Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood

open access: yes, 2007
Background During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients.
Thielmann, Matthias   +11 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

High-efficient white blood cell separation from whole blood using cascaded inertial microfluidics

open access: yes
White blood cells (WBCs) are a crucial component of the human immune system. WBCs contain invaluable information about the health status of the human body. Therefore, separating WBCs is indispensable for the diagnosis of many diseases in clinical setting.
Nguyen, Nam-Trung   +6 more
core   +1 more source

Overlapping White Blood Cell Segmentation And Counting On Microscopic Blood Cell Images

open access: yes, 2014
Overlapping white blood cell identification on microscopic blood cell images is proposed for increasing the accuracy of white blood cell segmentation and counting.
Chastine Fatichah   +3 more
core   +1 more source

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