Results 221 to 230 of about 385,480 (309)

Infectious morbidity and white blood cell count associated with grade repetition and school absenteeism. [PDF]

Acta Paediatr
Villamor E, Beer RJ, Seeley AL, López-Arana S, Marín C, Mora-Plazas M.   +5 more
europepmc   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Association between baseline white blood cell count and future cardiovascular events in patients with stable coronary artery disease- Sub-analysis of the REAL-CAD trial. [PDF]

Am J Prev Cardiol
Okada K, Hibi K, Misumi T, Iwahashi N, Gohbara M, Uemura K, Iwata H, Fukumoto Y, Hiro T, Ozaki Y, Iimuro S, Sakuma I, Hokimoto S, Miyauchi K, Matsuyama Y, Nakagawa Y, Ogawa H, Daida H, Shimokawa H, Saito Y, Kimura T, Matsuzaki M, Kimura K, Nagai R.   +23 more
europepmc   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Genetic variants associated with white blood cell count amongst individuals with sickle cell disease. [PDF]

Br J Haematol
Cintho Ozahata M, Guo Y, Gomes I, Malta B, Belisário A, Amorim L, Teles D, Park M, Kelly S, Sabino EC, Page GP, Custer B, Dinardo CL, International Component of the NHLBI Recipient Epidemiology and Donor Evaluation Study (REDS‐III) and for the TOPMed (NHLBI TransOmics for Precision Medicine) SCD working.   +13 more
europepmc   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Association of white blood cell count with one-year mortality after cardiac arrest. [PDF]

Resusc Plus
Seppä AMJ, Skrifvars MB, Vuopio H, Raj R, Reinikainen M, Pekkarinen PT.   +5 more
europepmc   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Comment on "Differential synovial fluid white blood cell count for the diagnosis of chronic peri-prosthetic joint infection - a systematic review and meta-analysis" by Sabater-Martos et al. (2025). [PDF]

J Bone Jt Infect
van Egmond PW, van der Jagt OP, Kuiper JWP.   +2 more
europepmc   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source